Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625277 | 1.00 | CES2 (0.37) | CES2ACHECES1IDO1DHODH | |
| SCHEMBL7715361 | 1.00 | CES2 (0.37) | CES2ACHECES1IDO1DHODH | |
| SCHEMBL18740114 | 0.98 | CES2 (0.38) | CES2ACHECES1IDO1DHODH | |
| SCHEMBL14390213 | 0.98 | CES2 (0.38) | CES2ACHECES1IDO1DHODH | |
| SCHEMBL18740110 | 0.98 | CES2 (0.38) | CES2ACHECES1IDO1DHODH | |
| SCHEMBL2592388 | 0.80 | ALDH1A1 (0.46) | CES2ACHECES1ALDH1A1MAPT | |
| SCHEMBL4624472 | 0.80 | HPGD (0.40) | ALDH1A1 | |
| SCHEMBL2592394 | 0.80 | ALDH1A1 (0.46) | CES2ACHECES1ALDH1A1MAPT | |
| SCHEMBL4624468 | 0.80 | HPGD (0.40) | ALDH1A1 | |
| SCHEMBL18655710 | 0.78 | IDO1 (0.37) | IDO1DHODHALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067121-B1 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2008-05-28 | — | — | EP | disclosed |
| US-6235911-B1 | 5-aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-1067121-A2 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | Mitsui Chemicals, Inc. (JP) | 2001-01-10 | — | — | EP | disclosed |