Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625215 | 0.83 | NPC1 (0.48) | PLATL3MBTL1POLBSMN1; SMN2MEN1 | |
| SCHEMBL4625129 | 0.79 | KDM4E (0.47) | PLATPOLBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL31735685 | 0.78 | POLB (0.45) | L3MBTL1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4625019 | 0.78 | POLB (0.49) | L3MBTL1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL27735788 | 0.76 | POLB (0.44) | L3MBTL1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20552140 | 0.70 | L3MBTL1 (0.46) | L3MBTL1POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL20552377 | 0.70 | LMNA (0.46) | L3MBTL1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20551667 | 0.69 | CYP1A2 (0.46) | L3MBTL1POLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL20550873 | 0.68 | NPC1 (0.54) | L3MBTL1SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL20551655 | 0.68 | LMNA (0.48) | L3MBTL1POLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067121-B1 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2008-05-28 | — | — | EP | disclosed |
| CN-1154639-C | 5-aminopyrazole-4-carboxylic ester derivatives and its preparing method | ������ѧ��ʽ���� | 2004-06-23 | — | — | CN | disclosed |
| US-6235911-B1 | 5-aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| CN-1280127-A | 5-aminopyrazole-4-carboxylic ester derivatives and its preparing method | MITSUI CHEMICAL IND CO LTD (JP) | 2001-01-17 | — | — | CN | disclosed |
| EP-1067121-A2 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | Mitsui Chemicals, Inc. (JP) | 2001-01-10 | — | — | EP | disclosed |