SCHEMBL4625969

SCHEMBL4625969

CCCOc1cc(C)ccc1P(=O)(C(=O)c1c(C)cc(C)cc1C)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
ALDH1A1 P00352 7/20 0.40
MAPT P10636 3/20 0.40
GAA P10253 1/20 0.40
MAPK1 P28482 1/20 0.40
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 5/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
PPARA Q07869 2/20 0.38
TTR P02766 1/20 0.38
CYP2C8 P10632 1/20 0.38
CHRM1 P11229 1/20 0.38
ADRA1A P35348 1/20 0.38
PPARG P37231 1/20 0.38
HTR2B P41595 1/20 0.38
SLCO1B3 Q9NPD5 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CISD1 Q9NZ45 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29660607 1.00 TSHR (0.42) TSHRALDH1A1MAPTGAAMAPK1
SCHEMBL29053717 0.87 NPC1 (0.41) TSHRALDH1A1MAPTGAATDP1
SCHEMBL444479 0.86 ITGB1 (0.46) TSHRITGB1ITGA4
SCHEMBL29389044 0.86 ITGB1 (0.46) TSHRITGB1ITGA4
SCHEMBL4707486 0.84 L3MBTL1 (0.42) TSHRALDH1A1MAPTHPGDSMN1; SMN2
SCHEMBL150337 0.84 ITGB1 (0.49) TSHRITGB1ITGA4
SCHEMBL8536848 0.84 L3MBTL1 (0.44) ALDH1A1MAPTMAPK1HPGDSMN1; SMN2
SCHEMBL4625245 0.83 ITGB1 (0.48) TSHRITGB1ITGA4
SCHEMBL4624645 0.83 ITGB1 (0.48) TSHRITGB1ITGA4
SCHEMBL29660598 0.83 ITGB1 (0.48) TSHRITGB1ITGA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP claimed
US-6737216-B2 TO FORM A RELIEF SURFACE E.I. DU PONT DE NEMOURS AND COMPANY 2004-05-18 US claimed
US-20020123003-A1 To form a relief surface E.I. DU PONT DE NEMOURS AND COMPANY 2002-09-05 US claimed
EP-1215044-A2 A laser engravable flexographic printing element and a method for forming a printing plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP claimed
CN-110114376-B Curable composition, method for producing cured product, cured product thereof, and adhesive using same 株式会社ADEKA 2022-06-14 CN disclosed
EP-3339331-B1 COMPOSITION ADEKA CORP (JP) 2022-02-16 EP disclosed
CN-108419438-B Coloring composition 株式会社艾迪科 2021-10-01 CN disclosed
CN-112154167-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-12-29 CN disclosed
CN-111566173-A Coating composition, method for curing the composition, barrier film, and method for producing cured product 株式会社艾迪科 2020-08-21 CN disclosed
CN-111315828-A Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2020-06-19 CN disclosed
CN-107636024-B Composition comprising a metal oxide and a metal oxide 株式会社艾迪科 2020-06-19 CN disclosed
WO-2020021969-A1 COMPOSITION, CURED PRODUCT, OPTICAL FILTER, AND PRODUCTION METHOD FOR CURED PRODUCT 株式会社ADEKA 2020-01-30 WO disclosed
EP-3339331-A1 COMPOSITION Adeka Corporation (JP) 2018-06-27 EP disclosed
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP disclosed
US-20020123003-A1 To form a relief surface E.I. DU PONT DE NEMOURS AND COMPANY 2002-09-05 US disclosed
EP-1215044-A2 A laser engravable flexographic printing element and a method for forming a printing plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP disclosed
US-5965776-A PHOTOINITIATORS FOR THE PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED COMPOUNDS CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-10-12 US disclosed
US-5767169-A STORAGE STABLE, NONHYDROLYZING CIBA SPECIALTY CHEMICALS CORPORATION (US) 1998-06-16 US disclosed