SCHEMBL4707486

SCHEMBL4707486

CCCOc1cc(C)ccc1P(=O)(C(=O)c1c(OCC)cccc1OCC)C(=O)c1c(OCC)cccc1OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.42
MAPT P10636 4/20 0.42
RAB9A P51151 1/20 0.42
ATM Q13315 1/20 0.42
KCNMA1 Q12791 1/20 0.40
HPGD P15428 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
KCNK3 O14649 2/20 0.38
KCNK9 Q9NPC2 2/20 0.38
PPARD Q03181 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ALDH1A1 P00352 1/20 0.37
NPBWR1 P48145 1/20 0.37
MCHR1 Q99705 1/20 0.37
KMT2A Q03164 1/20 0.36
MRGPRX1 Q96LB2 1/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8536848 0.91 L3MBTL1 (0.44) L3MBTL1MAPTRAB9AHPGDTDP1
SCHEMBL4625969 0.84 TSHR (0.42) L3MBTL1MAPTRAB9AHPGDTDP1
SCHEMBL29660607 0.84 TSHR (0.42) L3MBTL1MAPTRAB9AHPGDTDP1
SCHEMBL29053717 0.77 NPC1 (0.41) MAPTRAB9ATDP1TSHRALDH1A1
SCHEMBL4624663 0.75 MAPT (0.43) L3MBTL1MAPTRAB9AATMKCNMA1
SCHEMBL5144192 0.73 THRB (0.47)
SCHEMBL4710769 0.72 THRA (0.48)
SCHEMBL5043176 0.72 ITGB1 (0.43)
SCHEMBL7627834 0.71 GGPS1 (0.46)
SCHEMBL29715644 0.71 GGPS1 (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP claimed
US-6737216-B2 TO FORM A RELIEF SURFACE E.I. DU PONT DE NEMOURS AND COMPANY 2004-05-18 US claimed
US-20020123003-A1 To form a relief surface E.I. DU PONT DE NEMOURS AND COMPANY 2002-09-05 US claimed
EP-1215044-A2 A laser engravable flexographic printing element and a method for forming a printing plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP claimed
EP-1215044-B1 A laser engravable flexographic printing element and a method for forming a printing plate from the element DU PONT (US) 2008-05-21 EP disclosed
US-20020123003-A1 To form a relief surface E.I. DU PONT DE NEMOURS AND COMPANY 2002-09-05 US disclosed
EP-1215044-A2 A laser engravable flexographic printing element and a method for forming a printing plate from the element E.I. DU PONT DE NEMOURS AND COMPANY (US) 2002-06-19 EP disclosed