Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 6/20 | 0.56 |
| ▸ | THRB | P10828 | 6/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304176 | 0.82 | TDP1 (0.78) | TDP1ALDH1A1MAPK1L3MBTL1APP | |
| Ammonia Solution, Strong SCHEMBL28588274 | 0.81 | TDP1 (0.75) | TDP1ALDH1A1MAPK1L3MBTL1APP | |
| Bicarbonate SCHEMBL7699565 | 0.81 | TDP1 (0.75) | TDP1ALDH1A1MAPK1L3MBTL1APP | |
| SCHEMBL28207503 | 0.81 | TDP1 (0.75) | TDP1ALDH1A1MAPK1L3MBTL1APP | |
| SCHEMBL1879757 | 0.80 | TDP1 (0.64) | TDP1ALDH1A1MAPK1L3MBTL1APP | |
| SCHEMBL56986 | 0.80 | TDP1 (0.59) | TDP1ALOX5ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL305392 | 0.80 | TDP1 (0.68) | TDP1ALOX5ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL8526866 | 0.79 | GAA (0.52) | TDP1ALOX5ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL27957232 | 0.79 | ALDH1A1 (0.53) | THRATHRBTDP1ALDH1A1MAPK1 | |
| SCHEMBL16049214 | 0.78 | CYP4F2 (0.54) | THRATHRBTDP1ALOX5APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242622-B1 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECH RES LTD (GB) | 2008-06-18 | — | — | EP | disclosed |
| US-7169554-B2 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | GEN-PROBE INCORPORATED (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030082713-A1 | Monitoring oligonucleotide binding processes using chemiluminescence quenching | THIRD WAVE TECHNOLOGIES, INC. | 2003-05-01 | — | — | US | disclosed |
| EP-1242622-A2 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | Molecular Light Technology Research Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001042497-A9 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECH RES LTD (GB) | 2002-06-06 | — | — | WO | disclosed |
| WO-2001042497-A2 | MONITORING OLIGONUCLEOTIDE BINDING PROCESSES USING CHEMILUMINESCENCE QUENCHING | MOLECULAR LIGHT TECHNOLOGY RESEARCH LIMITED (GB) | 2001-06-14 | — | — | WO | disclosed |