Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46209 | 0.93 | TSHR (0.33) | TSHRSMN1; SMN2KDM4ECUL4A | |
| SCHEMBL19139726 | 0.92 | TSHR (0.34) | TSHRSMN1; SMN2KDM4ECUL4A | |
| SCHEMBL12070327 | 0.92 | L3MBTL1 (0.32) | — | |
| SCHEMBL12070200 | 0.90 | SMN1; SMN2 (0.33) | TSHRSMN1; SMN2KDM4E | |
| SCHEMBL12070326 | 0.89 | TSHR (0.33) | TSHRCUL4A | |
| SCHEMBL46174 | 0.89 | KDM4E (0.34) | TSHRKDM4E | |
| SCHEMBL12070325 | 0.87 | TSHR (0.36) | TSHR | |
| SCHEMBL46160 | 0.86 | — | — | |
| SCHEMBL46098 | 0.86 | TSHR (0.34) | TSHRSMN1; SMN2KDM4ECUL4A | |
| SCHEMBL12071668 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2575469-B1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-03-14 | — | — | EP | disclosed |
| EP-2575472-B1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA USING SPIROHETEROCYCLIC PYRROLIDINE DIONE DERIVATIVES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-07-19 | — | — | EP | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9485989-B2 | Method of controlling neonicotinoid resistant hemiptera | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-08 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9462808-B2 | Pesticidal compositions | SYNGENTA PARTICIPANTS AG (CH) | 2016-10-11 | — | — | US | disclosed |
| US-9018135-B2 | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-28 | — | — | US | disclosed |
| US-9018135-B2 | Pesticidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2015-04-28 | — | — | US | disclosed |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | US | disclosed |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2014-02-27 | — | — | US | disclosed |
| EP-2352376-B1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-01-01 | — | — | EP | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-08-29 | — | — | US | disclosed |
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2013-06-13 | — | — | US | disclosed |
| WO-2011151249-A2 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151248-A1 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| WO-2011151247-A2 | PESTICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-12-08 | — | — | WO | disclosed |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-15 | — | — | US | disclosed |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2011-09-15 | — | — | US | disclosed |
| WO-2010063670-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150394-A1 | PESTICIDAL COMPOSITIONS | ACHE, DDT, GAP43 | TSHR 1200/4885SMN1; SMN2 141/4885KDM4E 3139/4885 |
| US-20130225411-A1 | PESTICIDAL COMPOSITIONS | DDT, CIP2A, CYP51A1 | TSHR 458/4885SMN1; SMN2 3383/4885KDM4E 2377/4885 |
| US-20140057930-A1 | METHOD OF CONTROLLING NEONICOTINOID RESISTANT HEMIPTERA | DDT, NAMPT, NISCH | TSHR 1645/4885SMN1; SMN2 852/4885KDM4E 2344/4885 |
| US-20110224079-A1 | SPIROHETEROCYCLIC N-OXYAMIDES AS PESTICIDES | DDT, ODC1, ACHE | TSHR 2206/4885SMN1; SMN2 1062/4885KDM4E 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.