Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12949853 | 0.91 | ESR1 (0.37) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL29636737 | 0.83 | GABRA1 (0.43) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL2861909 | 0.83 | GABRA1 (0.43) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL12949854 | 0.81 | P2RX3 (0.36) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL8060858 | 0.79 | GABRA1 (0.45) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL9068743 | 0.77 | GABRA1 (0.43) | GABRA1GABRB2CYP1A2CYP3A4LMNA | |
| SCHEMBL2603176 | 0.76 | KMT2A (0.41) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL141647 | 0.75 | CA1 (0.60) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL4575432 | 0.75 | P2RX3 (0.58) | GABRA1GABRB2P2RX3P2RX2CYP1A2 | |
| SCHEMBL31257131 | 0.75 | CA1 (0.60) | GABRA1GABRB2P2RX3P2RX2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2277623-A2 | Polymeric phosphorus-containing compositions and their use in hydrocyanation, unsaturated nitrile isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2011-01-26 | — | — | EP | disclosed |
| EP-1448298-B1 | POLYMERIC PHOSPHORUS-CONTAINING COMPOSITIONS AND THEIR USE IN HYDROCYANATION, UNSATURATED NITRILE ISOMERIZATION AND HYDROFORMYLATION REACTIONS | INVISTA TECH SARL (CH) | 2010-09-22 | — | — | EP | disclosed |
| EP-1586598-B1 | Process for preparation of polymeric, phosphorus-containing compositions | INVISTA TECH SARL (CH) | 2009-09-09 | — | — | EP | disclosed |
| EP-1571172-B1 | Polymeric, phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA TECH SARL (CH) | 2008-10-22 | — | — | EP | disclosed |
| EP-1448620-B1 | SUPPORTED BIS(PHOSPHORUS)LIGANDS AND THEIR USE IN THE CATALYSIS | INVISTA TECH SARL (CH) | 2008-06-04 | — | — | EP | disclosed |
| EP-1905511-A2 | Phosphorus-containing compositions and their use in hydrocyanation, isomerization and hydroformylation reactions | INVISTA Technologies S.à.r.l. (CH) | 2008-04-02 | — | — | EP | disclosed |
| EP-1214975-B1 | Supported bis(phosphorus) ligands and use thereof in hydrocyanation processes | INVISTA TECH SARL (US) | 2006-03-15 | — | — | EP | disclosed |
| US-6984604-B2 | Supported bis(phosphorus) ligands and their use in the catalysis | INVISTA NORTH AMERICA S.A.R.L. (US) | 2006-01-10 | — | — | US | disclosed |
| CN-1617892-A | Supported bis(phosphorus) ligands and their use in the catalysis | DU PONT (US) | 2005-05-18 | — | — | CN | disclosed |
| EP-1448620-A1 | SUPPORTED BIS(PHOSPHORUS)LIGANDS AND THEIR USE IN THE CATALYSIS | E. I. du Pont de Nemours and Company (US) | 2004-08-25 | — | — | EP | disclosed |
| EP-0911339-A1 | Method of making phosphorochloridites | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5874641-A | HYDROFORMYLATION CATALYST COMPRISING RHODIUM AND A BIDENTATE PHOSPHITE LIGAND HAVING A 2,2'-DIHYDROXYL-1,1'-BINAPHTHALENE BRIDGE; REACTING CARBON MONOXIDE AND HYDROGEN WITH UNSATURATED HYDROCARBONS, NITRILES OR ESTERS; SELECTIVITY | DSM N.V. (NL) | 1999-02-23 | — | — | US | disclosed |
| WO-1999006146-A2 | SUPPORTED DIOLS AND SUPPORTED BIS(PHOSPHORUS) LIGANDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1999006345-A1 | IMPROVED PROCESS OF PREPARATION OF LINEAR ALDEHYDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-02-11 | — | — | WO | disclosed |
| EP-0888274-A1 | PROCESS TO PREPARE A TERMINAL ALDEHYDE | DSM N.V. (NL) | 1999-01-07 | — | — | EP | disclosed |
| US-5821378-A | USING A NICKEL COMPLEX HAVING MULTIDENTATE PHOSPHITE LIGANDS AS CATALYST; LIQUID PHASE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-10-13 | — | — | US | disclosed |
| US-5696280-A | USING A CATALYST CONTAINING PHOSPHITE GROUPS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-09 | — | — | US | disclosed |
| EP-0804412-A1 | HYDROCYANATION OF DIOLEFINS AND ISOMERIZATION OF NONCONJUGATED 2-ALKYL-3-MONOALKENENITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1997033854-A1 | PROCESS TO PREPARE A TERMINAL ALDEHYDE | DSM N.V. (NL) | 1997-09-18 | — | — | WO | disclosed |
| WO-1996022968-A1 | HYDROCYANATION OF DIOLEFINS AND ISOMERIZATION OF NONCONJUGATED 2-ALKYL-3-MONOALKENENITRILES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-01 | — | — | WO | disclosed |