Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634443 | 0.90 | POLB (0.51) | POLBMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL31486428 | 0.81 | KLK7 (0.49) | KMT2AMEN1 | |
| SCHEMBL5065670 | 0.81 | KLK7 (0.49) | KMT2AMEN1 | |
| SCHEMBL8669568 | 0.81 | KLK7 (0.49) | KMT2AMEN1 | |
| SCHEMBL823090 | 0.79 | POLB (0.55) | POLBDNMT1MAPTKMT2AKDM4E | |
| SCHEMBL817748 | 0.79 | POLB (0.55) | POLBDNMT1MAPTKMT2AKDM4E | |
| SCHEMBL7699900 | 0.77 | KLK7 (0.43) | KMT2AKDM4EALDH1A1CYP3A4 | |
| SCHEMBL823096 | 0.75 | POLB (0.55) | POLBMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL22482842 | 0.75 | POLB (0.52) | POLBDNMT1MAPTKMT2AKDM4E | |
| SCHEMBL818231 | 0.75 | POLB (0.55) | POLBMAPTKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1529776-B1 | Amino acid derivatives and sweetening agent | AJINOMOTO KK (JP) | 2008-03-05 | — | — | EP | disclosed |
| EP-1529776-A2 | Amino acid derivatives and sweetening agent | Ajinomoto Co., Inc. (JP) | 2005-05-11 | — | — | EP | disclosed |