Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 8/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 7/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK1 | P23458 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31486428 | 1.00 | KLK7 (0.49) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL5065670 | 1.00 | KLK7 (0.49) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL7699900 | 0.93 | KLK7 (0.43) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL8667026 | 0.92 | KLK7 (0.48) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL7697794 | 0.88 | KLK7 (0.39) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL7697791 | 0.88 | KLK7 (0.39) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL30387086 | 0.88 | KLK7 (0.45) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL22446555 | 0.88 | KLK7 (0.45) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL12643706 | 0.88 | KLK7 (0.45) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL31486524 | 0.88 | KLK7 (0.45) | KLK7KLK5PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5707991-A | TREATMENT OF NERVOUS SYSTEM DISORDERS, PARKINSON'S DISEASE | RHONE-POULENC RORER S.A. (FR) | 1998-01-13 | — | — | US | disclosed |