Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 7/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 6/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065670 | 0.93 | KLK7 (0.49) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL31486428 | 0.93 | KLK7 (0.49) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL8669568 | 0.93 | KLK7 (0.49) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL7701458 | 0.91 | MMP13 (0.38) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL7697791 | 0.86 | KLK7 (0.39) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL7697794 | 0.86 | KLK7 (0.39) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL8667026 | 0.85 | KLK7 (0.48) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL5204187 | 0.83 | OPRK1 (0.44) | KLK7KLK5KDM4EALDH1A1 | |
| SCHEMBL11994280 | 0.82 | KLK7 (0.43) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL12888044 | 0.82 | KLK7 (0.46) | KLK7KLK5PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002014261-A2 | 4-SUBSTITUTED D-GLUTAMIC ACID DERIVATIVES FOR USE AS ANTIBIOTIC | ELI LILLY AND COMPANY (US) | 2002-02-21 | — | — | WO | disclosed |