Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.48 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.39 |
| ▸ | TET3 | O43151 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336542 | 0.95 | — | — | |
| SCHEMBL28064758 | 0.95 | RNPEP (0.52) | TP53RNPEPSLC7A5OR51E2SMN1; SMN2 | |
| SCHEMBL185354 | 0.95 | — | — | |
| SCHEMBL361589 | 0.95 | — | — | |
| Methane SCHEMBL11205299 | 0.92 | RNPEP (0.50) | TP53RNPEPSLC7A5OR51E2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL3345131 | 0.92 | RNPEP (0.50) | TP53RNPEPSLC7A5OR51E2SMN1; SMN2 | |
| SCHEMBL28300024 | 0.92 | RNPEP (0.50) | TP53RNPEPSLC7A5OR51E2SMN1; SMN2 | |
| SCHEMBL11476606 | 0.92 | RNPEP (0.50) | TP53RNPEPSLC7A5OR51E2SMN1; SMN2 | |
| Leucine SCHEMBL20898433 | 0.81 | SLC7A5 (0.78) | RNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL30970939 | 0.80 | TET2 (0.71) | RNPEPSLC7A5TET2KDM4AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1281766-B1 | Process for producing polyester, process for producing substituted alpha-hydroxy acid, and Clostridium beijerinckii strain HICA432 | CANON KK (JP) | 2008-06-04 | — | — | EP | disclosed |
| US-7273734-B2 | Process for producing a polyester | CANON KABUSHIKI KAISHA (JP) | 2007-09-25 | — | — | US | disclosed |
| US-20050143574-A1 | Process for producing a polyester | CANON KABUSHIKI KAISHA (JP) | 2005-06-30 | — | — | US | disclosed |
| US-20030027294-A1 | Process for producing polyester, process for producing substituted a-hydroxy acid, and clostridium beijerinckii strain hica432 | CANON KABUSHIKI KAISHA (JP) | 2003-02-06 | — | — | US | disclosed |
| EP-1281766-A2 | Process for producing polyester, process for producing substituted alpha-hydroxy acid, and Clostridium beijerinckii strain HICA432 | CANON KABUSHIKI KAISHA (JP) | 2003-02-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143574-A1 | Process for producing a polyester | CYP8B1, HSD11B1, HPD | TP53 4550/4885RNPEP 1716/4885SLC7A5 3186/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.