Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902452 | 0.86 | SLC6A2 (0.52) | OPRM1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL8028845 | 0.86 | SLC6A2 (0.52) | OPRM1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL8028820 | 0.86 | SLC6A2 (0.52) | OPRM1SLC6A2SLC6A4SLC6A3LMNA | |
| SCHEMBL4632472 | 0.84 | CHRNB2 (0.43) | SLC6A2SLC6A4SLC6A3LMNAHRH3 | |
| SCHEMBL10808280 | 0.84 | SLC6A2 (0.36) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2761798 | 0.82 | SLC6A2 (0.56) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL902225 | 0.82 | SLC6A2 (0.56) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4967524 | 0.82 | SLC6A2 (0.56) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3349919 | 0.81 | SLC6A2 (0.56) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL4739317 | 0.81 | SLC6A2 (0.56) | OPRM1OPRD1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917237-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | Teva Pharmaceutical Industries Ltd (IL) | 2008-05-07 | — | — | EP | claimed |
| WO-2008013994-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-31 | — | — | WO | claimed |
| EP-1917237-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | Teva Pharmaceutical Industries Ltd (IL) | 2008-05-07 | — | — | EP | disclosed |
| WO-2008013994-A2 | PROCESSES FOR THE SYNTHESIS OF O-DESMETHYLVENLAFAXINE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-01-31 | — | — | WO | disclosed |