Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8028845 | 0.86 | SLC6A2 (0.52) | LMNACHRM2CHRM1SLC6A2SLC6A4 | |
| SCHEMBL902452 | 0.86 | SLC6A2 (0.52) | LMNACHRM2CHRM1SLC6A2SLC6A4 | |
| SCHEMBL8028820 | 0.86 | SLC6A2 (0.52) | LMNACHRM2CHRM1SLC6A2SLC6A4 | |
| SCHEMBL4627006 | 0.84 | OPRM1 (0.39) | LMNASLC6A2SLC6A4SLC6A3HRH3 | |
| SCHEMBL4085148 | 0.83 | ALOX5 (0.44) | LMNASLC6A2SLC6A3 | |
| SCHEMBL4736496 | 0.83 | SLC6A2 (0.57) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL902225 | 0.82 | SLC6A2 (0.56) | LMNAKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2761798 | 0.82 | SLC6A2 (0.56) | LMNAKMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4967524 | 0.82 | SLC6A2 (0.56) | LMNAKMT2ASLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL3349919 | 0.81 | SLC6A2 (0.56) | LMNAKMT2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924251-A1 | TOPICAL FORMULATIONS CONTAINING O-DESMETHYL VENLAFAXINE (ODV) OR ITS SALTS | Wyeth a Corporation of the State of Delaware (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007030537-A1 | TOPICAL FORMULATIONS CONTAINING O-DESMETHYL VENLAFAXINE (ODV) OR ITS SALTS | WYETH (US) | 2007-03-15 | — | — | WO | disclosed |