Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.61 |
| ▸ | CSF1R | P07333 | 14/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4627414 | 0.92 | PDE4B (0.57) | PDE4BCSF1REGFRERBB2 | |
| SCHEMBL4627679 | 0.90 | PDE4B (0.55) | PDE4BCSF1R | |
| SCHEMBL4950158 | 0.87 | PDE4B (0.73) | PDE4BCSF1REGFRERBB2 | |
| SCHEMBL4627145 | 0.83 | PDE4B (0.77) | PDE4BCSF1R | |
| SCHEMBL4627626 | 0.82 | PDE4B (0.59) | PDE4BCSF1R | |
| SCHEMBL4627716 | 0.81 | PDE4B (0.60) | PDE4BCSF1R | |
| SCHEMBL4951386 | 0.78 | PDE4B (0.74) | PDE4BCSF1REGFR | |
| SCHEMBL4627622 | 0.78 | PDE4B (0.73) | PDE4BCSF1R | |
| SCHEMBL4627499 | 0.77 | PDE4B (0.74) | PDE4BCSF1R | |
| SCHEMBL4948827 | 0.76 | PDE4B (0.71) | PDE4BCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673086-B1 | 4-AMINOQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS PDE4 INHIBITORS | GLAXO GROUP LTD (GB) | 2008-01-23 | — | — | EP | claimed |