Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL729315 | 0.81 | MEN1 (0.54) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL4626663 | 0.79 | HTR1A (0.51) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL9951781 | 0.77 | MEN1 (0.55) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL28622872 | 0.76 | MEN1 (0.51) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL3949886 | 0.76 | MEN1 (0.78) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL18438857 | 0.76 | MEN1 (0.61) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL28284853 | 0.76 | MEN1 (0.59) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL1012890 | 0.76 | NCF1 (0.63) | KDM4EMAPTCCR6 | |
| SCHEMBL731221 | 0.76 | KDM4E (0.56) | KDM4EMAPTCCR6MEN1KMT2A | |
| SCHEMBL19830909 | 0.75 | MEN1 (0.53) | KDM4EMAPTCCR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | claimed |