Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7899276 | 0.97 | KCNN4 (0.48) | KCNN4MAPK1CES1ALDH1A1TAAR1 | |
| SCHEMBL1430201 | 0.79 | KCNN4 (0.50) | KCNN4MAPK1CES1ALDH1A1TAAR1 | |
| SCHEMBL3478682 | 0.77 | MAPK1 (0.48) | KCNN4MAPK1CES1ALDH1A1TAAR1 | |
| SCHEMBL2700899 | 0.77 | MAPK1 (0.48) | KCNN4MAPK1CES1ALDH1A1TAAR1 | |
| SCHEMBL9545629 | 0.75 | KCNN4 (0.46) | KCNN4MAPK1CES1ALDH1A1TAAR1 | |
| SCHEMBL16487248 | 0.73 | KCNN4 (0.39) | KCNN4MAPK1CES1TAAR1KIF11 | |
| SCHEMBL28820080 | 0.73 | KCNN4 (0.30) | KCNN4 | |
| SCHEMBL30183453 | 0.73 | KCNN4 (0.44) | KCNN4MAPK1CES1ALDH1A1TAAR1 | |
| SCHEMBL28401721 | 0.73 | KCNN4 (0.44) | KCNN4MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL2065992 | 0.73 | TAAR1 (0.52) | KCNN4MAPK1CES1TAAR1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3543236-B1 | METHOD FOR PREPARING AVIBACTAM INTERMEDIATE | XINFA PHARMACEUTICAL CO LTD (CN) | 2022-02-16 | — | — | EP | claimed |
| CN-107827817-B | Method for synthesizing formamide derivative through molybdenum catalytic formylation reaction | 湘潭大学 | 2020-03-13 | — | — | CN | claimed |
| WO-2019075984-A1 | METHOD FOR PREPARING AVIBACTAM INTERMEDIATE | 新发药业有限公司 | 2019-04-25 | — | — | WO | claimed |
| CN-103709161-B | One-dimensional organic semiconductor nanowire with fluorescence and photoconduction dual response for organic amine gas as well as preparation method and application of nanowire | CHINESE ACAD INST CHEMISTRY | 2015-05-20 | — | — | CN | claimed |
| CN-103709161-A | One-dimensional organic semiconductor nanowire with fluorescence and photoconduction dual response for organic amine gas as well as preparation method and application of nanowire | CHINESE ACAD INST CHEMISTRY | 2014-04-09 | — | — | CN | claimed |
| WO-2012033956-A1 | COGNITION ENHANCING COMPOUNDS AND COMPOSITIONS, METHODS OF MAKING, AND METHODS OF TREATING | MITHRIDION, INC. (US) | 2012-03-15 | — | — | WO | claimed |
| JP-6025163-A | — | — | None | — | — | JP | disclosed |
| EP-4731689-A1 | METHOD FOR THE PRODUCTION OF THERMOPLASTIC POLYOXAZOLIDINONE | Covestro Deutschland AG (DE) | 2026-04-29 | — | — | EP | disclosed |
| US-20260062427-A1 | Bicyclic Ureas As Kinase Inhibitors | INCYTE CORP (US) | 2026-03-05 | — | — | US | disclosed |
| US-20250387397-A1 | SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME LLC (US) | 2025-12-25 | — | — | US | disclosed |
| EP-3883576-B1 | SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | MERCK SHARP & DOHME LLC (US) | 2025-12-17 | — | — | EP | disclosed |
| EP-4200353-B1 | METHOD FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | COVESTRO DEUTSCHLAND AG (DE) | 2025-11-19 | — | — | EP | disclosed |
| EP-4448605-B1 | PROCESS FOR THE PRODUCTION OF A THERMOPLASTIC POLYOXAZOLIDINONE | COVESTRO DEUTSCHLAND AG (DE) | 2025-11-19 | — | — | EP | disclosed |
| US-4166816-A | CYCLIZATION | SMITHKLINE CORPORATION (US) | 1979-09-04 | — | — | US | disclosed |
| US-4162250-A | INTERMEDIATES FOR BACTERICIDES | SMITHKLINE CORPORATION (US) | 1979-07-24 | — | — | US | disclosed |
| US-4144333-A | Monocyclic beta-lactams with antibacterial activity | SMITHKLINE CORPORATION (US) | 1979-03-13 | — | — | US | disclosed |
| US-4122262-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-10-24 | — | — | US | disclosed |
| US-4103086-A | 8-Oxo-4-thia-1-azabicyclo (4.2.0)-oct-2-ene derivatives | SMITHKLINE CORPORATION (US) | 1978-07-25 | — | — | US | disclosed |
| US-4089956-A | 7-Acylamino-8-oxo-3-oxa-1-azabicyclo[4.2.0]octane-2-carboxylic acid derivatives and bactericidal compositions and use thereof | SMITHKLINE CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |
| US-4072674-A | FOR CEPHALOSPORIN CONGENERS | SMITHKLINE CORPORATION (US) | 1978-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062427-A1 | Bicyclic Ureas As Kinase Inhibitors | OXSR1, NCOR1, NR0B1 | KCNN4 2409/4885MAPK1 32/4885CES1 928/4885 |
| US-20250387397-A1 | SUBSTITUTED AMINO TRIAZOLOPYRIMIDINE AND AMINO TRIAZOLOPYRAZINE ADENOSINE RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE | ADORA2A, ADORA2B, ADORA1 | KCNN4 758/4885MAPK1 3417/4885CES1 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.