Sugi Predict

Sugi Predict / Compounds / SCHEMBL4628008

SCHEMBL4628008

SCHEMBL4628008

CCCCOC(=O)c1ccc(CC)cc1C(=O)OCCCC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 7/20 0.67
▸ TDP1 Q9NUW8 2/20 0.67
▸ L3MBTL1 Q9Y468 2/20 0.67
▸ MAPK1 P28482 3/20 0.60
▸ CYP3A4 P08684 3/20 0.60
▸ TP53 P04637 1/20 0.60
▸ ALDH1A1 P00352 6/20 0.59
▸ LMNA P02545 3/20 0.58
▸ HSD17B10 Q99714 2/20 0.54
▸ ESR1 P03372 4/20 0.50
▸ CYP1A2 P05177 2/20 0.50
▸ CYP2C19 P33261 2/20 0.50
▸ CYP2D6 P10635 1/20 0.50
▸ NR1H2 P55055 1/20 0.50
▸ RNASEL Q05823 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ CYP2C9 P11712 1/20 0.49
▸ PDE4D Q08499 1/20 0.49
▸ KDM4E B2RXH2 2/20 0.48
▸ POLB P06746 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4628608 0.95 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL28884835 0.95 TSHR (0.68) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL4627367 0.94 TSHR (0.69) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL13737267 0.92 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL4628347 0.90 TSHR (0.63) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL4628503 0.90 TSHR (0.55) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL4628360 0.90 TSHR (0.55) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL4628171 0.90 TSHR (0.55) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL7853559 0.89 TSHR (0.61) TSHRTDP1L3MBTL1MAPK1CYP3A4
SCHEMBL30822757 0.88 TSHR (0.52) TSHRTDP1L3MBTL1MAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3204159-B1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS GRACE W R & CO (US) 2020-12-16 — — EP disclosed
EP-2701843-B1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS W R GRACE & CO -CONN (US) 2017-11-29 — — EP disclosed
EP-3204159-A1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS W.R. Grace & CO. - CONN. (US) 2017-08-16 — — EP disclosed
US-9714302-B2 Process for preparing spherical polymerization catalyst components for use in olefin polymerizations W. R. Grace & Co.—Conn. (US) 2017-07-25 — — US disclosed
US-9403924-B2 Process of production of large and spherical polymerization catalyst and use of same in olefin polymerizations BASF CORPORATION (US) 2016-08-02 — — US disclosed
WO-2016057634-A1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS BASF CORPORATION (US) 2016-04-14 — — WO disclosed
US-20160102156-A1 PROCESS FOR PREPARING SPHERICAL POLYMERIZATION CATALYST COMPONENTS FOR USE IN OLEFIN POLYMERIZATIONS W. R. GRACE & CO.-CONN. 2016-04-14 — — US disclosed
US-20150361194-A1 PROCESS OF PRODUCTION OF LARGE AND SPHERICAL POLYMERIZATION CATALYST AND USE OF SAME IN OLEFIN POLYMERIZATIONS W. R. GRACE & CO.-CONN. 2015-12-17 — — US disclosed
WO-2015191851-A1 PROCESS OF PRODUCTION OF LARGE AND SPHERICAL POLYMERIZATION CATALYST AND USE OF SAME IN OLEFIN POLYMERIZATIONS BASF CORPORATION (US) 2015-12-17 — — WO disclosed
CN-103619475-A Emulsion process for improved large spherical polypropylene catalysts BASF SE 2014-03-05 — — CN disclosed
US-20120277090-A1 EMULSION PROCESS FOR IMPROVED LARGE SPHERICAL POLYPROPYLENE CATALYSTS BASF CORPORATION (US) 2012-11-01 — — US disclosed
EP-1188739-B1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO LTD (JP) 2008-08-13 — — EP disclosed
EP-1209172-B1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION TOHO TITANIUM CO LTD (JP) 2008-07-02 — — EP disclosed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 — — US disclosed
US-6670497-B2 Dialkyl (at least one of which is a C4-8 tertiary alkyl) ester of an alkyl- or halo-substituted phthalic acid; used in an olefin polymerization catalyst TOHO TITANIUM CO., LTD. (JP) 2003-12-30 — — US disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 — — US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 — — US disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 — — EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX TSHR 4817/4885TDP1 2416/4885L3MBTL1 4720/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.