Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 13/20 | 1.00 |
| ▸ | NR1H2 | P55055 | 11/20 | 1.00 |
| ▸ | MLYCD | O95822 | 6/20 | 0.62 |
| ▸ | RORC | P51449 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4417331 | 0.83 | NR1H2 (0.71) | NR1H3NR1H2 | |
| SCHEMBL1382028 | 0.82 | NR1H2 (1.00) | NR1H3NR1H2MLYCDRORC | |
| SCHEMBL11881187 | 0.79 | NR1H2 (0.62) | NR1H3NR1H2 | |
| SCHEMBL2080647 | 0.79 | NR1H3 (1.00) | NR1H3NR1H2MLYCDRORC | |
| SCHEMBL4629232 | 0.77 | NR1H2 (1.00) | NR1H3NR1H2MLYCD | |
| SCHEMBL28281535 | 0.77 | NR1H2 (0.62) | NR1H3NR1H2 | |
| SCHEMBL2945131 | 0.77 | MLYCD (1.00) | NR1H3NR1H2MLYCDRORC | |
| SCHEMBL18596506 | 0.76 | NR1H3 (0.61) | NR1H3NR1H2MLYCD | |
| SCHEMBL6493549 | 0.76 | MLYCD (0.63) | NR1H3NR1H2MLYCD | |
| SCHEMBL6493890 | 0.76 | NR1H3 (0.60) | NR1H3NR1H2MLYCDRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014148438-A1 | THERAPEUTIC AGENT FOR HEPATITIS C WHICH COMPRISES 4-(1,1,1,3,3,3-HEXAFLUORO-2-HYDROXYPROPAN-2-YL)BENZENE DERIVATIVE | 国立大学法人岡山大学 (JP) | 2014-09-25 | — | — | WO | disclosed |
| EP-1917233-B1 | ANILINOHEXAFLUOROISOPROPANOL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-12-17 | — | — | EP | disclosed |
| EP-1917233-B1 | ANILINOHEXAFLUOROISOPROPANOL COMPOUNDS | SMITHKLINE BEECHAM CORP (US) | 2008-12-17 | — | — | EP | disclosed |
| US-20080221176-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-11 | — | — | US | disclosed |
| US-20080221176-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-11 | — | — | US | disclosed |
| US-20080221176-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-09-11 | — | — | US | disclosed |
| EP-1917233-A1 | CHEMICAL COMPOUNDS | SmithKline Beecham Corporation (US) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007024954-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-01 | — | — | WO | disclosed |
| WO-2007024954-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221176-A1 | Chemical Compounds | NR1H3, NR1H2, NR1H4 | NR1H3 1/4885NR1H2 2/4885MLYCD 1065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.