Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 8/20 | 0.63 |
| ▸ | DRD2 | P14416 | 7/20 | 0.63 |
| ▸ | RAD52 | P43351 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.57 |
| ▸ | HTR2A | P28223 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | HRH2 | P25021 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10657526 | 0.88 | RAD52 (0.63) | DRD3DRD2RAD52RECQLADRA2A | |
| SCHEMBL563307 | 0.83 | RAD52 (0.79) | DRD3DRD2RAD52RECQLADRA2A | |
| Hydrochloric Acid SCHEMBL10652670 | 0.81 | RAD52 (0.77) | DRD3DRD2RAD52RECQLADRA2A | |
| SCHEMBL15075331 | 0.81 | DRD2 (0.55) | DRD3DRD2RAD52RECQLADRA2A | |
| SCHEMBL15996427 | 0.79 | DRD3 (0.56) | DRD3DRD2RAD52RECQLADRA2A | |
| Hydrochloric Acid SCHEMBL11395621 | 0.79 | MAPT (0.62) | DRD3DRD2RAD52RECQLADRA2A | |
| SCHEMBL7292227 | 0.79 | DRD2 (0.62) | DRD3DRD2RAD52RECQLADRA2A | |
| SCHEMBL5059578 | 0.78 | DRD2 (0.55) | DRD3DRD2RAD52RECQLADRA2A | |
| SCHEMBL5059513 | 0.78 | DRD2 (0.56) | DRD3DRD2RAD52RECQLADRA2A | |
| SCHEMBL7294939 | 0.78 | DRD2 (0.61) | DRD3DRD2RAD52ADRA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-63170315-A | — | — | None | — | — | JP | disclosed |
| EP-1877374-A1 | ORGANIC NITRIC OXIDE ENHANCING SALTS OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS, COMPOSITIONS AND METHODS OF USE | Nitromed, Inc. (US) | 2008-01-16 | — | — | EP | disclosed |
| WO-2006102071-A1 | ORGANIC NITRIC OXIDE ENHANCING SALTS OF ANGIOTENSIN CONVERTING ENZYME INHIBITORS, COMPOSITIONS AND METHODS OF USE | NITROMED, INC. (US) | 2006-09-28 | — | — | WO | disclosed |
| JP-S63170315-A | GROWTH HORMONE RELEASING AGENT OF 6-ARYL-2-AMINO- 5,6,7,8-TETRAHYDRO-4H-THIAZOLO(5,4-D)AZEPINE AS EFFECTIVE COMPONENT | BOEHRINGER INGELHEIM KG | 1988-07-14 | — | — | JP | disclosed |