Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 7/20 | 0.55 |
| ▸ | DRD3 | P35462 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.52 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | HRH1 | P35367 | 1/20 | 0.52 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.52 |
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15996427 | 0.88 | DRD3 (0.56) | DRD2DRD3MAPTHRH3LMNA | |
| SCHEMBL4628121 | 0.81 | DRD3 (0.63) | DRD2DRD3MAPTHRH3LMNA | |
| SCHEMBL5059513 | 0.79 | DRD2 (0.56) | DRD2DRD3MAPTHRH3LMNA | |
| Hydrochloric Acid SCHEMBL11395621 | 0.77 | MAPT (0.62) | DRD2DRD3MAPTHRH3LMNA | |
| Hydrochloric Acid SCHEMBL10657526 | 0.77 | RAD52 (0.63) | DRD2DRD3MAPTHRH3LMNA | |
| SCHEMBL5059578 | 0.76 | DRD2 (0.55) | DRD2DRD3MAPTHRH3LMNA | |
| SCHEMBL5059575 | 0.76 | DRD2 (0.52) | DRD2DRD3MAPTHRH3LMNA | |
| SCHEMBL563307 | 0.75 | RAD52 (0.79) | DRD2DRD3MAPTHRH3LMNA | |
| SCHEMBL13884476 | 0.75 | TSHR (0.44) | DRD2DRD3MAPTKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL10652670 | 0.74 | RAD52 (0.77) | DRD2DRD3MAPTHRH3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170137489-A1 | Process for the Synthesis of Therapeutic Peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2017-05-18 | — | — | US | disclosed |
| US-9475837-B2 | Process for the synthesis of therapeutic peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2016-10-25 | — | — | US | disclosed |
| US-20150045534-A1 | Process for the Synthesis of Therapeutic Peptides | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2015-02-12 | — | — | US | disclosed |
| US-8822442-B2 | Somatostatin-dopamine chimeric analogs | IPSEN PHARMA S.A.S. (FR) | 2014-09-02 | — | — | US | disclosed |
| EP-1617856-B1 | SOMATOSTATIN-DOPAMINE CHIMERIC ANALOGS | IPSEN PHARMA (FR) | 2014-01-15 | — | — | EP | disclosed |
| WO-2013093639-A1 | PROCESS FOR THE SYNTHESIS OF THERAPEUTIC PEPTIDES | IPSEN MANUFACTURING IRELAND LIMITED (IE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045534-A1 | Process for the Synthesis of Therapeutic Peptides | MAX, VIP, SFPQ | DRD2 4642/4885DRD3 4178/4885MAPT 1661/4885 |
| US-20170137489-A1 | Process for the Synthesis of Therapeutic Peptides | NPEPPS, DNPEP, QPCT | DRD2 4692/4885DRD3 4408/4885MAPT 1243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.