Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 18/20 | 0.60 |
| ▸ | KIF23 | Q02241 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4628175 | 0.84 | KIF11 (0.59) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4968235 | 0.84 | KIF11 (0.65) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4629019 | 0.83 | KIF11 (0.58) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4629070 | 0.82 | KIF11 (0.57) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4628053 | 0.82 | KIF11 (0.59) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4498513 | 0.81 | KIF11 (0.66) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4511477 | 0.81 | KIF11 (0.66) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4376437 | 0.80 | KIF11 (0.78) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL4363754 | 0.80 | KIF11 (0.65) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 | |
| SCHEMBL5752668 | 0.80 | KIF11 (0.70) | KIF11KIF23KCNH2MAP1LC3BCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620092-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-04-16 | — | — | EP | claimed |
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | claimed |
| EP-1620092-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | claimed |
| WO-2004100873-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-25 | — | — | WO | claimed |
| EP-1620092-A4 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS INC (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
| US-20080021079-A1 | Compounds, Compositions, and Methods | CYTOKINETICS, INC. | 2008-01-24 | — | — | US | disclosed |
| EP-1620092-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004100873-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021079-A1 | Compounds, Compositions, and Methods | ALPP, PCNA, MKI67 | KIF11 538/4885KIF23 246/4885KCNH2 2321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.