Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOST | Q9BQB4 | 1/20 | 0.92 |
| ▸ | FPGS | Q05932 | 2/20 | 0.83 |
| ▸ | GART | P22102 | 5/20 | 0.70 |
| ▸ | DHFR | P00374 | 1/20 | 0.63 |
| ▸ | ATIC | P31939 | 3/20 | 0.61 |
| ▸ | MTHFD1 | P11586 | 2/20 | 0.59 |
| ▸ | MTHFD2 | P13995 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofolate SCHEMBL21248573 | 1.00 | SOST (0.92) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL23630632 | 1.00 | SOST (0.92) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL30051444 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL29870853 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL29435894 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL8030 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL2691812 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL9879710 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL159231 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC | |
| Tetrahydrofolate SCHEMBL4535491 | 0.96 | SOST (1.00) | SOSTFPGSGARTDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917006-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT Patent & Licence Trading Ltd. (GB) | 2008-05-07 | — | — | EP | claimed |
| WO-2006136454-A2 | USE OF INHIBITORS OF N-METHYL TRANSFERASES FOR THE THERAPY OF PARKINSON'S DISEASE | PLT PATENT & LICENCE TRADING LTD. (GB) | 2006-12-28 | — | — | WO | claimed |