SCHEMBL4628330

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4628946	0.96	CRHR1 (0.41)	CRHR1SCN9ATXNRD1EIF4ERUNX1
	SCHEMBL6348992	0.88	CRHR1 (0.51)	CRHR1SCN9ATXNRD1EIF4ERUNX1
	SCHEMBL4628316	0.87	CRHR1 (0.43)	CRHR1SCN9ATXNRD1EIF4ERUNX1
	SCHEMBL4881928	0.85	CRHR1 (0.54)	CRHR1SCN9ATXNRD1EIF4ERUNX1
	SCHEMBL4626672	0.83	CRHR1 (0.48)	CRHR1SCN9ARUNX1GPR3SCN5A
	SCHEMBL6343330	0.78	SCN9A (0.43)	CRHR1SCN9ARUNX1ABL1GPR3
	SCHEMBL14183023	0.78	CRHR1 (0.49)	CRHR1SCN9ATXNRD1RUNX1GPR3
	SCHEMBL4878756	0.78	CRHR1 (0.55)	CRHR1SCN9ARUNX1GPR3SCN5A
	SCHEMBL26092497	0.76	ALOX5AP (0.43)	CRHR1SCN9AMEN1KMT2A
	SCHEMBL4882817	0.75	CRHR1 (0.59)	CRHR1SCN9ARUNX1GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.