Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2127604 | 0.84 | DPP4 (0.32) | GAADPP4 | |
| Hydrochloric Acid SCHEMBL6399729 | 0.84 | DPP4 (0.32) | GAADPP4 | |
| SCHEMBL2127142 | 0.82 | DPP4 (0.32) | GAAKMT2ADPP4ADRA2C | |
| Hydrochloric Acid SCHEMBL2126545 | 0.82 | GAA (0.36) | GAADPP4 | |
| SCHEMBL2127202 | 0.80 | GAA (0.37) | GAADPP4 | |
| Hydrochloric Acid SCHEMBL2537390 | 0.65 | — | — | |
| SCHEMBL2129200 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL6505708 | 0.64 | GAA (0.34) | GAA | |
| Hydrochloric Acid SCHEMBL6495609 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL6496555 | 0.63 | GAA (0.33) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1428515-B1 | Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a surfactant; methods and uses | OREAL (FR) | 2008-07-02 | — | — | EP | claimed |