Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.60 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.58 |
| ▸ | ERN1 | O75460 | 4/20 | 0.57 |
| ▸ | FYN | P06241 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864586 | 0.84 | ALDH1A1 (0.66) | TNFRSF1AERN1FYNKDM4EALDH1A1 | |
| SCHEMBL14819133 | 0.84 | SMPD3 (0.57) | TNFRSF1ASMPD3ERN1FYNKDM4E | |
| SCHEMBL26414626 | 0.81 | ALDH1A1 (0.52) | TNFRSF1ASMPD3ERN1KDM4EALDH1A1 | |
| SCHEMBL23097942 | 0.80 | KCNH2 (0.64) | ERN1KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL5960645 | 0.78 | TNFRSF1A (0.58) | TNFRSF1AERN1KDM4EALDH1A1MEN1 | |
| SCHEMBL6068103 | 0.78 | ERN1 (0.64) | ERN1MAPT | |
| SCHEMBL29744559 | 0.78 | ERN1 (0.64) | ERN1MAPT | |
| SCHEMBL6990108 | 0.78 | TNFRSF1A (0.60) | TNFRSF1AERN1KDM4EALDH1A1RAB9A | |
| SCHEMBL28278107 | 0.78 | ALDH1A1 (0.62) | TNFRSF1AERN1FYNKDM4EALDH1A1 | |
| SCHEMBL6067795 | 0.78 | ERN1 (0.54) | TNFRSF1ASMPD3ERN1FYNKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1631147-A4 | ALKOXY ALKYLSULFANYL PHENOLS | FLEXITRAL INC (US) | 2008-04-16 | — | — | EP | disclosed |
| US-20060189509-A1 | Alkoxy alkylsulfanyl phenols | FLEXITRAL, INC. | 2006-08-24 | — | — | US | disclosed |
| EP-1631147-A2 | ALKOXY ALKYLSULFANYL PHENOLS | Flexitral, Inc. (US) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004103962-A2 | ALKOXY ALKYLSULFANYL PHENOLS | FLEXITRAL, INC. (US) | 2004-12-02 | — | — | WO | disclosed |