Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15443876 | 0.80 | GNAI3 (0.33) | TSHRGNAI3GNAO1GNAI1TP53 | |
| SCHEMBL31638412 | 0.71 | GNAI3 (0.40) | TSHRGNAI3GNAO1GNAI1TP53 | |
| SCHEMBL30399713 | 0.70 | TSHR (0.45) | TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL31638118 | 0.69 | GNAI3 (0.45) | TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL29012623 | 0.68 | GNAI3 (0.44) | TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL31638212 | 0.67 | GNAI3 (0.50) | TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL4622935 | 0.66 | GNAI3 (0.53) | TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL29012621 | 0.66 | GNAI3 (0.49) | TSHRGNAI3GNAO1GNAI1 | |
| SCHEMBL409726 | 0.65 | — | — | |
| SCHEMBL22001207 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2012-03-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120065169-A1 | OLIGONUCLEOTIDE ANALOGUES HAVING MODIFIED INTERSUBUNIT LINKAGES AND/OR TERMINAL GROUPS | NSUN2, UPF1, RTCB | TSHR 2993/4885GNAI3 2137/4885GNAO1 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.