Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | STK17B | O94768 | 1/20 | 0.44 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29075992 | 0.86 | POLB (0.47) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL29168148 | 0.86 | NQO2 (0.57) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL1820623 | 0.86 | LMNA (0.61) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL4598153 | 0.85 | NQO2 (0.56) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL31250995 | 0.81 | NQO2 (0.56) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL1231492 | 0.81 | NQO2 (0.56) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL14691066 | 0.81 | DRD2 (0.45) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL6681403 | 0.80 | NQO2 (0.56) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL4381773 | 0.79 | NQO2 (0.61) | NQO2LMNAMEN1KMT2ATSHR | |
| SCHEMBL6676049 | 0.79 | IDO1 (0.55) | NQO2LMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924265-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | Genzyme Corporation (US) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022371-A2 | CHEMOKINE RECEPTOR BINDING COMPOUNDS | GENZYME CORPORATION (US) | 2007-02-22 | — | — | WO | disclosed |