Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.39 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5358422 | 0.84 | KDM4E (0.39) | CYP11B1CYP11B2GAACA12CA1 | |
| SCHEMBL2900162 | 0.83 | EPHX2 (0.44) | CYP11B1CYP11B2PGRAREPHX2 | |
| SCHEMBL4628852 | 0.83 | EPHX2 (0.46) | CYP11B1CYP11B2PGRAREPHX2 | |
| SCHEMBL26375160 | 0.82 | GPR3 (0.45) | GAACYP1A2 | |
| SCHEMBL17287109 | 0.81 | KCNJ11 (0.42) | ARGAA | |
| SCHEMBL179542 | 0.81 | GAA (0.47) | GAACA12CA1CA2CA7 | |
| SCHEMBL17286686 | 0.80 | HSD11B1 (0.45) | PGRARGAA | |
| SCHEMBL31193485 | 0.79 | CA12 (0.56) | CYP11B1CYP11B2PGRARGAA | |
| SCHEMBL7909509 | 0.79 | CA12 (0.56) | CYP11B1CYP11B2PGRARGAA | |
| SCHEMBL15305003 | 0.79 | CYP11B2 (0.59) | CYP11B1CYP11B2PGRAREPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019195159-A1 | PRODRUGS OF FUSED-BICYCLIC C5aR ANTAGONISTS | CHEMOCENTRYX, INC. (US) | 2019-10-10 | — | — | WO | disclosed |