⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139319 | 0.80 | MEN1 (0.40) | — | |
| SCHEMBL8865924 | 0.71 | — | — | |
| SCHEMBL4724773 | 0.70 | LMNA (0.35) | — | |
| SCHEMBL7772623 | 0.70 | PKM (0.37) | — | |
| SCHEMBL4947231 | 0.70 | — | — | |
| SCHEMBL1042812 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL29508586 | 0.67 | — | — | |
| SCHEMBL30675167 | 0.67 | — | — | |
| SCHEMBL40708 | 0.67 | — | — | |
| SCHEMBL30532723 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1918272-A1 | Pharmaceutically active compounds and methods of use | Wyeth a Corporation of the State of Delaware (US) | 2008-05-07 | — | — | EP | disclosed |
| US-20060270741-A1 | Pharmaceutically active compounds and methods of use | SCION PHARMACEUTICALS, INC. (US) | 2006-11-30 | — | — | US | disclosed |
| US-7041702-B1 | Pharmaceutically active compounds and methods of use | SCION PHARMACEUTICALS, INC. (US) | 2006-05-09 | — | — | US | disclosed |