Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TLR4 | O00206 | 1/20 | 0.41 |
| ▸ | TLR2 | O60603 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL563788 | 1.00 | NFE2L2 (0.58) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| Sulfuric Acid SCHEMBL28329173 | 0.98 | NFE2L2 (0.56) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| SCHEMBL1654497 | 0.89 | NFE2L2 (0.70) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| SCHEMBL1654495 | 0.89 | NFE2L2 (0.70) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| Sulfuric Acid SCHEMBL29699491 | 0.88 | NFE2L2 (0.49) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| Sulfuric Acid SCHEMBL1170799 | 0.88 | NFE2L2 (0.49) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| Sulfuric Acid SCHEMBL29157761 | 0.87 | NFE2L2 (0.47) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| Sulfuric Acid SCHEMBL29157758 | 0.87 | NFE2L2 (0.47) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| Sulfuric Acid SCHEMBL29652042 | 0.87 | NFE2L2 (0.47) | NFE2L2TRPA1HTTALOX5PTGS1 | |
| Water SCHEMBL28632016 | 0.87 | NFE2L2 (0.68) | NFE2L2TRPA1HTTALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108884091-B | Condensed heterocyclic compound and pest control agent | 日产化学株式会社 | 2021-04-13 | — | — | CN | disclosed |
| CN-111955469-A | Pesticide for cucumbers and cucumber pest control method | 武汉麦世吉科技有限公司 | 2020-11-20 | — | — | CN | disclosed |
| CN-107207506-B | Condensed heterocyclic compound and pest control agent | 日产化学株式会社 | 2020-06-05 | — | — | CN | disclosed |
| CN-109068648-A | Fungicidal or bactericidal composition and method for controlling diseases | 日产化学株式会社 | 2018-12-21 | — | — | CN | disclosed |
| CN-108884091-A | Condensed heterocyclic compouds and noxious organism control agent | 日产化学株式会社 | 2018-11-23 | — | — | CN | disclosed |
| CN-105960169-B | Bactericidal or bactericidal composition and method for controlling disease | 日产化学工业株式会社 | 2018-09-28 | — | — | CN | disclosed |
| CN-103358749-B | Original edition of lithographic printing plate | 富士胶片株式会社 | 2018-01-30 | — | — | CN | disclosed |
| CN-107207506-A | Condensed heterocyclic compouds and noxious organism control agent | 日产化学工业株式会社 | 2017-09-26 | — | — | CN | disclosed |
| CN-102119143-B | Amide derivative, pest control agent containing the same, and method of using the pest control agent | 三井化学AGRO株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-106659160-A | Insecticide, miticide, nematicide, molluscicide, disinfectant, or bactericide composition, and pest control method | 日产化学工业株式会社 | 2017-05-10 | — | — | CN | disclosed |
| CN-102119144-B | The preparation method of amide derivatives | MITSUI CHEMICALS AGRO, INC. (JP) | 2015-12-02 | — | — | CN | disclosed |
| CN-105061248-A | Amide derivative, pest control agent containing the amide derivative and use of the pest control agent | MITSUI CHEMICALS AGRO INC | 2015-11-18 | — | — | CN | disclosed |
| CN-102558082-B | Isoxazoline-substituted benzamide compound prepare intermediate | NISSAN CHEMICAL INDUSTRIES CO., LTD. (JP) | 2015-09-30 | — | — | CN | disclosed |
| CN-102532048-B | Isoxazoline-substituted benzamide compound and pesticide | NISSAN CHEMICAL IND LTD | 2015-06-24 | — | — | CN | disclosed |
| CN-104428282-A | Oxime-substituted amide compound and pest control agent | NISSAN CHEMICAL IND LTD | 2015-03-18 | — | — | CN | disclosed |
| EP-1943901-A2 | Method of controlling plant disease | Nissan Chemical Industries, Ltd. (JP) | 2008-07-16 | — | — | EP | disclosed |
| EP-1661697-B1 | Printing method employing a processless printing plate. | KONICA MINOLTA MED & GRAPHIC (JP) | 2008-05-07 | — | — | EP | disclosed |
| EP-1661697-A1 | Printing method employing a processless printing plate. | Konica Minolta Medical & Graphic, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |