Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.48 |
| ▸ | NR3C2 | P08235 | 13/20 | 0.48 |
| ▸ | PGR | P06401 | 7/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3538840 | 0.87 | NR3C1 (0.45) | NR3C1NR3C2PGR | |
| SCHEMBL4629304 | 0.83 | NR3C1 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL3533752 | 0.80 | NR3C2 (0.52) | NR3C1NR3C2PGR | |
| SCHEMBL3652962 | 0.78 | NR3C1 (0.51) | NR3C1NR3C2PGRAR | |
| SCHEMBL3654876 | 0.78 | NR3C1 (0.53) | NR3C1NR3C2PGRAR | |
| SCHEMBL5527417 | 0.75 | NR3C1 (0.62) | NR3C1NR3C2PGR | |
| SCHEMBL5776235 | 0.75 | NR3C1 (0.42) | NR3C1NR3C2PGR | |
| SCHEMBL5529473 | 0.74 | NR3C1 (0.59) | NR3C1NR3C2PGR | |
| SCHEMBL3953152 | 0.74 | NR3C1 (0.54) | NR3C1NR3C2PGRAR | |
| SCHEMBL5521694 | 0.73 | NR3C1 (0.72) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188666-A1 | LINEAR PHENYL-SUBSTITUTED INDAZOLES AND INDOLES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | ASTRAZENECA AB (SE) | 2008-08-07 | — | — | US | disclosed |
| WO-2008055710-A1 | INDOLE AND INDAZOLE DERIVATIVES AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT | 2008-05-15 | — | — | WO | disclosed |
| EP-1921067-A1 | Indole and indazole derivatives as anti-inflammatory agents | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188666-A1 | LINEAR PHENYL-SUBSTITUTED INDAZOLES AND INDOLES, A PROCESS FOR THEIR PRODUCTION AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | IDO1, IL1B, IDO2 | NR3C1 1243/4885NR3C2 1183/4885PGR 1611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.