Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629495 | 0.94 | CYP1A2 (0.30) | — | |
| SCHEMBL14911108 | 0.74 | CAPN1 (0.34) | — | |
| SCHEMBL16869542 | 0.72 | TYMP (0.34) | — | |
| SCHEMBL11191548 | 0.71 | GPR84 (0.30) | — | |
| SCHEMBL9428445 | 0.70 | MGLL (0.31) | TSHR | |
| Dodecane SCHEMBL28106124 | 0.68 | HTT (0.36) | TSHR | |
| SCHEMBL12468222 | 0.68 | CAPN1 (0.35) | — | |
| SCHEMBL4702245 | 0.67 | — | — | |
| SCHEMBL18272457 | 0.67 | — | — | |
| SCHEMBL6476566 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |