Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407286 | 0.78 | KMT2A (0.53) | KMT2A | |
| SCHEMBL27947005 | 0.78 | KMT2A (0.43) | JAK3KMT2A | |
| SCHEMBL14505992 | 0.78 | HPGD (0.60) | NPC1RAB9AJAK3KMT2A | |
| SCHEMBL1318504 | 0.78 | HPGD (0.60) | NPC1RAB9AJAK3KMT2A | |
| SCHEMBL6371533 | 0.77 | HDAC1 (0.50) | NPC1ALDH1A1KMT2A | |
| SCHEMBL4266412 | 0.77 | KCNK3 (0.61) | CYP1A2NPC1RAB9AKCNK3KCNK9 | |
| Hydrochloric Acid SCHEMBL440964 | 0.77 | KMT2A (0.56) | KMT2A | |
| SCHEMBL29060808 | 0.77 | HPGD (0.56) | NPC1RAB9AKMT2AHTR2C | |
| SCHEMBL3879671 | 0.77 | NPC1 (0.47) | NPC1RAB9AATMKMT2A | |
| SCHEMBL29060806 | 0.77 | HPGD (0.56) | NPC1RAB9AKMT2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116606247-A | Imide compound and preparation method and application thereof | 温州医科大学 | 2023-08-18 | — | — | CN | disclosed |
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |