SCHEMBL4629685

SCHEMBL4629685

CCCc1cn[nH]c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630135 0.86
SCHEMBL21263656 0.85 NOS2 (0.44)
SCHEMBL458851 0.85 TDP1 (0.44)
SCHEMBL10948171 0.83 PTGS2 (0.47)
SCHEMBL20539012 0.83 PTGS2 (0.47)
SCHEMBL26999527 0.83 PTGS2 (0.47)
SCHEMBL2541661 0.83 PTGS2 (0.47)
SCHEMBL24581986 0.80 PDCD1LG2 (0.41)
SCHEMBL24291858 0.78 NOS2 (0.36)
SCHEMBL19001245 0.78 HRH4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12419870-B2 Compositions and methods for immune cell modulation in adoptive immunotherapies FATE THERAPEUTICS, INC. (US) 2025-09-23 US disclosed
WO-2024246764-A1 NOVEL BENZAMIDE DERIVATIVE COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 삼진제약주식회사 2024-12-05 WO disclosed
WO-2024107658-A2 INHIBITORS OF TYK2 VYRNWY THERAPEUTICS, INC. (US) 2024-05-23 WO disclosed
WO-2024044344-A1 PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS, INC. (US) 2024-02-29 WO disclosed
WO-2024006841-A2 COMPOSITIONS FOR WEIGHT LOSS AND CANCER TREATMENT KNOWLEDGE PHARMACEUTICALS INC. (US) 2024-01-04 WO disclosed
EP-3784669-B1 PTERIDINONE COMPOUNDS AND USES THEREOF VERTEX PHARMA (US) 2023-10-25 EP disclosed
US-20230279013-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2023-09-07 US disclosed
US-20230279014-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2023-09-07 US disclosed
WO-2023118238-A1 PHARMACEUTICAL COMPOSITIONS FOR INDUCING HDAC7 EXPRESSION FUNDACIÓ INSTITUT DE RECERCA CONTRA LA LEUCÈMIA JOSEP CARRERAS (ES) 2023-06-29 WO disclosed
WO-2023096928-A1 HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. (US) 2023-06-01 WO disclosed
CN-101437810-A Quinazoline derivatives ASTRAZENECA AB (SE) 2009-05-20 CN disclosed
CN-101432276-A Quinoline derivatives ASTRAZENECA AB (SE) 2009-05-13 CN disclosed
WO-2008057336-A2 HETEROCYCLYL-SUBSTITUTED ANTI-HYPERCHOLESTEROLEMIC COMPOUNDS MERCK & CO., INC. (US) 2008-05-15 WO disclosed
EP-1919907-A2 HETEROCYCLIC COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2008-05-14 EP disclosed
WO-2007026959-A2 DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2007-03-08 WO disclosed
WO-2007020521-A1 PYRIDOYRAZINONES AS PDE-5 INHIBITORS PHARMACIA & UPJOHN COMPANY LLC (US) 2007-02-22 WO disclosed
US-4247630-A ADDING A TRIHALOETHANOL, PYRAZOLE, PYRIDINE, 4-METHYLPYRIDINE, THIOUREA, OR ISOBUTYRAMIDE TO SUPPRESS CREEP REACTIONS IN AN OXIDOREDUCTASE-ENZYME SYSTEM BOEHRINGER MANNHEIM GMBH (DE) 1981-01-27 US disclosed
EP-0003284-B1 FUNGICIDAL AND BACTERICIDAL COMPOSITIONS CONTAINING 3-AZOLYL-BENZOTRIAZINES AND -BENZOTRIAZINE 1-OXIDES AND THEIR USE AGAINST PLANT DISEASES BAYER AG (DE) 1981-01-07 EP disclosed
US-4239760-A Combating fungi and bacteria with 3-azolyl-benzo-1,2,4-triazines and 1-oxides thereof BAYER AKTIENGESELLSCHAFT (DE) 1980-12-16 US disclosed
EP-0003284-A1 Fungicidal and bactericidal compositions containing 3-azolyl-benzotriazines and -benzotriazine 1-oxides and their use against plant diseases BAYER AG (DE) 1979-08-08 EP disclosed