⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8580441 | 0.74 | — | — | |
| SCHEMBL3839622 | 0.72 | — | — | |
| SCHEMBL7585020 | 0.72 | — | — | |
| SCHEMBL1674738 | 0.72 | — | — | |
| SCHEMBL4431241 | 0.70 | — | — | |
| SCHEMBL8624273 | 0.67 | ADH1B (0.36) | — | |
| SCHEMBL8923107 | 0.65 | ADH1B (0.38) | — | |
| SCHEMBL6037198 | 0.64 | KIF11 (0.33) | — | |
| SCHEMBL8924793 | 0.64 | EPHX1 (0.41) | — | |
| SCHEMBL28678335 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917270-A2 | PROCESS FOR PREPARING BETA-LACTAMASE INHIBITORS | Wyeth (US) | 2008-05-07 | — | — | EP | disclosed |
| US-20070149499-A1 | Process for preparing beta-lactamase inhibitors | WYETH (US) | 2007-06-28 | — | — | US | disclosed |
| WO-2007024859-A2 | PROCESS FOR PREPARING BETA-LACTAMASE INHIBITORS | WYETH (US) | 2007-03-01 | — | — | WO | disclosed |