SCHEMBL4629705

SCHEMBL4629705

CCCCCCCC1=CCC(=O)O1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.37
BACE1 P56817 1/20 0.37
CDC25A P30304 6/20 0.37
CDC25B P30305 6/20 0.37
CDC25C P30307 5/20 0.37
GPR84 Q9NQS5 7/20 0.35
CYP1A2 P05177 2/20 0.35
CYP1A1 P04798 1/20 0.33
ALOX5 P09917 1/20 0.33
FAAH O00519 1/20 0.33
MGLL Q99685 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3021386 1.00 ACHE (0.37) ACHEBACE1CDC25ACDC25BCDC25C
SCHEMBL2315804 1.00 ACHE (0.37) ACHEBACE1CDC25ACDC25BCDC25C
SCHEMBL704205 0.98 ACHE (0.34) ACHEBACE1CDC25ACDC25BCDC25C
Hexanoate SCHEMBL27802806 0.86 SCD (0.51) CDC25ACDC25BCDC25CGPR84
SCHEMBL9992284 0.81 FNTA (0.37)
SCHEMBL7054062 0.80 CYP1A2 (0.34) ACHEBACE1CDC25ACDC25BCDC25C
SCHEMBL9264130 0.76 ACHE (0.40) ACHEBACE1CDC25ACDC25BCDC25C
SCHEMBL8780203 0.76 ACHE (0.40) ACHEBACE1CDC25ACDC25BCDC25C
SCHEMBL14751591 0.75 GPR84 (0.37) ACHEBACE1CDC25ACDC25BCDC25C
SCHEMBL11156027 0.74 ACHE (0.37) ACHEBACE1CDC25ACDC25BCDC25C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-11246484-A None JP disclosed
US-20080247966-A1 Compositions and Methods to Counteract Oral Malodour GIVAUDAN SA (CH) 2008-10-09 US disclosed
EP-1919566-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR Givaudan SA (CH) 2008-05-14 EP disclosed
WO-2007025401-A1 COMPOSITIONS AND METHODS TO COUNTERACT ORAL MALODOUR GIVAUDAN SA (CH) 2007-03-08 WO disclosed
EP-0911315-B1 Beta-ketoester GIVAUDAN SA (CH) 2003-06-11 EP disclosed
US-6348618-B1 PREPARING ORGANOLEPTIC OR ANTIMICROBIAL COMPOUNDS BY CONTACTING BETA-KETO ESTER WITH MATERIAL SELECTED FROM BACTERIA, ENZYMES, AND MATERIAL HAVING ACIDIC OR ALKALINE PH, ELEVATING TEMPERATURE, EXPOSING TO LIGHT GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2002-02-19 US disclosed
US-6222062-B1 USEFUL AS PRECURSORS FOR ORGANOLEPTIC COMPOUNDS, ESPECIALLY FOR FLAVORS, FRAGRANCES AND MASKING AGENTS AND ANTIMICROBIAL COMPOUNDS GIVAUDAN ROURE (INTERNATIONAL) SA (CH) 2001-04-24 US disclosed
JP-H11246484-A BETA-KETOESTER GIVAUDAN ROURE INTERNATL SA 1999-09-14 JP disclosed
EP-0911315-A1 Beta-ketoester Givaudan Roure (International) S.A. (CH) 1999-04-28 EP disclosed