Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 12/20 | 0.44 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247516 | 1.00 | RORC (0.44) | RORCMGLLJAK1KDM1AKDM4E | |
| SCHEMBL4629158 | 1.00 | RORC (0.44) | RORCMGLLJAK1KDM1AKDM4E | |
| SCHEMBL13201876 | 1.00 | RORC (0.44) | RORCMGLLJAK1KDM1AKDM4E | |
| SCHEMBL2714917 | 0.88 | RORC (0.44) | RORCMGLLJAK1KDM1A | |
| SCHEMBL12313218 | 0.88 | RORC (0.57) | RORCMGLL | |
| SCHEMBL23752795 | 0.88 | MGLL (0.54) | RORCMGLL | |
| SCHEMBL5242538 | 0.88 | RORC (0.57) | RORCMGLL | |
| SCHEMBL2712886 | 0.88 | RORC (0.57) | RORCMGLL | |
| SCHEMBL9951030 | 0.88 | RORC (0.57) | RORCMGLL | |
| SCHEMBL2975631 | 0.88 | RORC (0.44) | RORCMGLLJAK1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1917242-A1 | AZABICYCLO [3.1.0]HEXYLPHENYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2008-05-07 | — | — | EP | disclosed |
| WO-2007022935-A1 | AZABICYCLO [3.1.0] HEXYLPHENYL DERIVATIVES AS MODULATORS OF DOPAMINE D3 RECEPTORS | GLAXO GROUP LIMITED (GB) | 2007-03-01 | — | — | WO | disclosed |