Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GNPAT | O15228 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3783821 | 1.00 | ALDH1A1 (0.42) | ALDH1A1ADAMTS4MAPTPTGS2KDM4E | |
| SCHEMBL4629978 | 1.00 | ALDH1A1 (0.42) | ALDH1A1ADAMTS4MAPTPTGS2KDM4E | |
| SCHEMBL14288628 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTPTGS2KDM4ETHRB | |
| SCHEMBL22277301 | 0.83 | GNPAT (0.54) | ALDH1A1ADAMTS4MAPTPTGS2KDM4E | |
| SCHEMBL20231564 | 0.83 | GNPAT (0.54) | ALDH1A1ADAMTS4MAPTPTGS2KDM4E | |
| SCHEMBL14396604 | 0.83 | ADAMTS4 (0.37) | ALDH1A1ADAMTS4MAPTPTGS2CA1 | |
| SCHEMBL24664421 | 0.80 | ECE1 (0.39) | ALDH1A1MAPTPTGS2KDM4ETHRB | |
| SCHEMBL11191528 | 0.80 | SMN1; SMN2 (0.38) | ALDH1A1MAPTPTGS2KDM4ETHRB | |
| SCHEMBL15786204 | 0.78 | TSHR (0.39) | ALDH1A1MAPTPTGS2KDM4ETHRB | |
| SCHEMBL754156 | 0.78 | CA1 (0.42) | ALDH1A1ADAMTS4MAPTPTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1694630-B1 | METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM FINE CHEM AUSTRIA GMBH (AT) | 2008-05-07 | — | — | EP | disclosed |
| US-20070123589-A1 | Method for producing chiral or enantiomer-enriched beta-amino acids, aldehydes, ketones and gama-amino alcohols | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2007-05-31 | — | — | US | disclosed |
| EP-1694630-A1 | IMPROVED METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2006-08-30 | — | — | EP | disclosed |
| WO-2005063682-A1 | IMPROVED METHOD FOR PRODUCING CHIRAL OR ENANTIOMER-ENRICHED BETA-AMINO ACIDS, -ALDEHYDES, -KETONES AND GAMMA-AMINO ALCOHOLS | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO KG (AT) | 2005-07-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070123589-A1 | Method for producing chiral or enantiomer-enriched beta-amino acids, aldehydes, ketones and gama-amino alcohols | GLRA1, GLRB, GLRA2 | ALDH1A1 97/4885ADAMTS4 4836/4885MAPT 3948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.