SCHEMBL4630035

SCHEMBL4630035

ClCCCCc1cc[c]cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.33
MAOB P27338 2/20 0.32
THRA P10827 1/20 0.32
THRB P10828 1/20 0.32
IGF1R P08069 1/20 0.31
ALOX15 P16050 1/20 0.31
SIGMAR1 Q99720 3/20 0.31
HRH1 P35367 2/20 0.30
ESR1 P03372 2/20 0.30
ADRA2A P08913 2/20 0.30
ADORA3 P0DMS8 2/20 0.30
TACR2 P21452 2/20 0.30
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 2/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
SHBG P04278 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8844825 0.98 SIGMAR1 (0.34) MAOATHRATHRBSIGMAR1HRH1
SCHEMBL9078158 0.98 SIGMAR1 (0.34) MAOATHRATHRBSIGMAR1HRH1
SCHEMBL7493158 0.98 SIGMAR1 (0.34) MAOATHRATHRBSIGMAR1HRH1
SCHEMBL436245 0.93 GMNN (0.31) MAOASIGMAR1ALDH1A1LMNAHIF1A
SCHEMBL11803736 0.87 MAOA (0.40) MAOAMAOBIGF1RALOX15SIGMAR1
SCHEMBL11690401 0.85 SIGMAR1 (0.41) MAOAMAOBSIGMAR1HRH1ESR1
SCHEMBL28579175 0.85
SCHEMBL933764 0.82
SCHEMBL9135033 0.82 MAOB (0.44) MAOAMAOBTHRATHRBIGF1R
SCHEMBL23837667 0.79 ESR1 (0.44) MAOBTHRATHRBIGF1RALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103554168-B Epoxy radicals silicone hydride, its preparation method and the curable compositions comprising it 莫门蒂夫性能材料股份有限公司 2017-07-18 CN claimed
CN-101679624-B Process for preparing hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MAT INC 2012-07-04 CN claimed
CN-101679624-A Process for preparing hydrolyzable silylated polymers MOMENTIVE PERFORMANCE MAT INC 2010-03-24 CN claimed
CN-109755647-A A kind of magnesium battery electrolyte 麻城市天力科技有限公司 2019-05-14 CN disclosed
CN-105764885-B The production method of acid and free-radical generating agent and acid and free radical 富士胶片和光纯药株式会社 2018-11-09 CN disclosed
CN-107004906-A Magnesium-containing electrolyte 和光纯药工业株式会社 2017-08-01 CN disclosed
CN-103554168-B Epoxy radicals silicone hydride, its preparation method and the curable compositions comprising it 莫门蒂夫性能材料股份有限公司 2017-07-18 CN disclosed
CN-105764885-A Acid- and radical-generating agent and method for generating acid and radical 和光纯药工业株式会社 2016-07-13 CN disclosed
CN-103554168-A Epoxysilanes, processes for their manufacture and curable compositions containing same MOMENTIVE PERFORMANCE MAT INC 2014-02-05 CN disclosed
CN-101675063-B Epoxysilanes, process for their preparation and curable compositions containing them MOMENTIVE PERFORMANCE MAT INC 2013-11-13 CN disclosed
CN-102850336-A DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS OTSUKA PHARMA CO LTD 2013-01-02 CN disclosed
US-5037976-A Antimicrobial Agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-08-06 US disclosed
US-4898859-A 2-Oxa-isocephem compounds and compositions containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-02-06 US disclosed
CN-1030237-A BENZOHETEROCYCLIC COMPOUNDS OTSUKA PHARMA CO LTD (JP) 1989-01-11 CN disclosed
CN-88102161-A 2-oxa-isocephem compounds, compositions containing them and processes for their preparation 1988-10-05 CN disclosed
EP-0282895-A2 2-oxa-isocephem compounds, compositions containing same and processes for preparing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-09-21 EP disclosed
CN-88100986-A Aryl piperazinyl-alkylene phenyl base-heterogeneous ring compound 1988-09-21 CN disclosed
EP-0005053-B1 FLAME-RETARDANT ORGANIC PHOSPHATES, THEIR PRODUCTION, AND COMPOSITIONS CONTAINING THEM FMC Corporation (US) 1983-05-25 EP disclosed
US-4246169-A Flammable plastics containing a flame retardant amount of polyarylphosphates and the polyarylphosphates FMC CORPORATION (US) 1981-01-20 US disclosed
EP-0005053-A2 Flame-retardant organic phosphates, their production, and compositions containing them FMC Corporation (US) 1979-10-31 EP disclosed