Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | PLK1 | P53350 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5188423 | 0.92 | TP53 (0.64) | L3MBTL1TSHRTP53PLA2G4BGAA | |
| SCHEMBL7464498 | 0.87 | TP53 (0.73) | TSHRTP53PLA2G4BLMNAMAPT | |
| SCHEMBL7455421 | 0.87 | TP53 (0.73) | TSHRTP53PLA2G4BLMNAMAPT | |
| SCHEMBL6341040 | 0.84 | L3MBTL1 (0.68) | L3MBTL1PLK1TSHRTP53PLA2G4B | |
| SCHEMBL1465950 | 0.84 | PARP10 (0.66) | L3MBTL1PLK1PLA2G4BKDM4EALDH1A1 | |
| SCHEMBL175191 | 0.82 | TP53 (0.77) | L3MBTL1PLK1TSHRTP53PLA2G4B | |
| SCHEMBL1442973 | 0.82 | L3MBTL1 (0.78) | L3MBTL1PLK1TSHRTP53PLA2G4B | |
| SCHEMBL29538825 | 0.81 | L3MBTL1 (0.64) | L3MBTL1PLK1TSHRTP53PLA2G4B | |
| SCHEMBL8172219 | 0.81 | L3MBTL1 (0.74) | L3MBTL1PLK1TSHRTP53MAPT | |
| SCHEMBL7632695 | 0.81 | L3MBTL1 (0.74) | L3MBTL1PLK1TSHRTP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919481-A2 | THERAPY FOR NEUROLOGICAL DISEASES | Ares Trading S.A. (CH) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007014943-A2 | THERAPY FOR NEUROLOGICAL DISEASES | ARES TRADING S.A. (CH) | 2007-02-08 | — | — | WO | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |