Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19121463 | 0.82 | UBE2T (0.57) | UBE2TMAPK10LMNASMN1; SMN2CASP3 | |
| SCHEMBL13757324 | 0.82 | UBE2T (0.47) | UBE2TMAPK10LMNASMN1; SMN2CASP3 | |
| SCHEMBL17166225 | 0.81 | UBE2T (0.42) | UBE2TMAPK10LMNASMN1; SMN2CASP3 | |
| SCHEMBL23222239 | 0.80 | UBE2T (0.55) | UBE2TMAPK10LMNASMN1; SMN2CASP3 | |
| SCHEMBL18997084 | 0.80 | UBE2T (0.55) | UBE2TMAPK10LMNASMN1; SMN2CASP3 | |
| SCHEMBL28240593 | 0.80 | UBE2T (0.55) | UBE2TMAPK10LMNASMN1; SMN2KDM4E | |
| SCHEMBL18789253 | 0.78 | KDM4E (0.59) | UBE2TMAPK10LMNAKDM4EALDH1A1 | |
| SCHEMBL30630823 | 0.78 | UBE2T (0.54) | UBE2TMAPK10LMNASMN1; SMN2CASP3 | |
| SCHEMBL30401301 | 0.78 | UBE2T (0.57) | UBE2TMAPK10LMNASMN1; SMN2CASP3 | |
| SCHEMBL24409275 | 0.78 | UBE2T (0.54) | UBE2TMAPK10LMNASMN1; SMN2CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017112777-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC (US) | 2017-06-29 | — | — | WO | disclosed |
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | SHY Therapeutics LLC | 2017-06-22 | — | — | US | disclosed |
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |
| US-7579348-B2 | Derivatives of 8-substituted xanthines | PGXHEALTH, LLC (US) | 2009-08-25 | — | — | US | disclosed |
| US-7579348-B2 | Derivatives of 8-substituted xanthines | PGXHEALTH, LLC (US) | 2009-08-25 | — | — | US | disclosed |
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADENOSINE THERAPEUTICS, LLC | 2007-10-25 | — | — | US | disclosed |
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADENOSINE THERAPEUTICS, LLC | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249598-A1 | Derivatives of 8-substituted xanthines | ADORA2B, ADORA2A, ADORA3 | UBE2T 4130/4885MAPK10 3824/4885LMNA 2265/4885 |
| US-20170174699-A1 | COMPOUNDS FOR THE TREATMENT OF CANCER AND INFLAMMATORY DISEASE | MAPK6, MAP3K6, MAPK4 | UBE2T 3141/4885MAPK10 8/4885LMNA 3509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.