Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19943585 | 0.82 | — | — | |
| SCHEMBL2628904 | 0.82 | — | — | |
| SCHEMBL27751694 | 0.82 | SLC6A1 (0.31) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL26495534 | 0.82 | — | — | |
| Acetic Acid SCHEMBL28060482 | 0.79 | KDM4E (0.38) | KDM4EMAPTKMT2AATMCYP2D6 | |
| SCHEMBL5909288 | 0.77 | — | — | |
| SCHEMBL869800 | 0.77 | — | — | |
| SCHEMBL5328 | 0.77 | — | — | |
| SCHEMBL27272783 | 0.77 | SLC6A1 (0.33) | KDM4EMAPTKMT2AATMCYP2D6 | |
| Piperazine SCHEMBL28120340 | 0.76 | KDM4E (0.42) | KDM4EMAPTKMT2AATMCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |