Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510583 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL29364563 | 0.81 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL1831312 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL4865864 | 0.79 | PSMB5 (0.37) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL19214801 | 0.78 | HSP90AA1 (0.35) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL10715444 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL4685179 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL20061662 | 0.78 | ALDH1A1 (0.38) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL4324227 | 0.78 | HRH4 (0.41) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 | |
| SCHEMBL18462726 | 0.78 | KDM4E (0.38) | KDM4EALDH1A1SMN1; SMN2NLRP3CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102858186-B | Method for producing soluble and functional plant proteins, products obtained and uses | 罗盖特兄弟公司 | 2016-11-09 | — | — | CN | claimed |
| US-9951071-B2 | Dihydropyridone P1 as factor XIa inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2018-04-24 | — | — | US | disclosed |
| US-20110152236-A1 | AZETIDINE POLYSUBSTITUTED COMPOUNDS, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2011-06-23 | — | — | US | disclosed |
| EP-1919907-A2 | HETEROCYCLIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007026959-A2 | DERIVATIVES OF 4-PIPERAZIN-1-YL-4-BENZ0 [B] THIOPHENE SUITABLE FOR THE TREATMENT OF CNS DISORDERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-03-08 | — | — | WO | disclosed |
| US-6325860-B1 | HEATING MIXTURE INCLUDING HYDROXYKETONE, ALDEHYDE AND AMMONIUM HYDROXIDE FOR TIME AND UNDER CONDITIONS SUFFICIENT TO PROVIDE FLAVORFUL AND AROMATIC COMPOSITION | R. J. REYNOLDS TOBACCO COMPANY | 2001-12-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110152236-A1 | AZETIDINE POLYSUBSTITUTED COMPOUNDS, PREPARATION THEREOF, AND THERAPEUTIC APPLICATION THEREOF | C1R, TACR1, C1S | KDM4E 2499/4885ALDH1A1 521/4885SMN1; SMN2 2797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.