Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | SP1 | P08047 | 1/20 | 0.34 |
| ▸ | ILF3 | Q12906 | 1/20 | 0.34 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4630607 | 0.79 | KDM4E (0.37) | PSMB5KDM4ERAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL510583 | 0.77 | KDM4E (0.40) | PSMB5KDM4EALDH1A1SMN1; SMN2NLRP3 | |
| SCHEMBL29364563 | 0.77 | KDM4E (0.40) | PSMB5KDM4EALDH1A1SMN1; SMN2NLRP3 | |
| SCHEMBL27635497 | 0.76 | NLRP3 (0.36) | KDM4ENPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1831312 | 0.75 | KDM4E (0.41) | PSMB5KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL4266146 | 0.73 | KDM4E (0.42) | KDM4ERAB9AALDH1A1CYP1A2BIRC5 | |
| SCHEMBL18462726 | 0.73 | KDM4E (0.38) | PSMB5KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9474835 | 0.73 | KDM4E (0.50) | PSMB5KDM4EALDH1A1SMN1; SMN2NLRP3 | |
| SCHEMBL20061662 | 0.73 | ALDH1A1 (0.38) | PSMB5KDM4EALDH1A1SMN1; SMN2NLRP3 | |
| SCHEMBL4685179 | 0.73 | KDM4E (0.38) | PSMB5KDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7316826-B2 | Coffee aroma with improved stability | SYMRISE GMBH & CO. KG (DE) | 2008-01-08 | — | — | US | claimed |
| US-20040202767-A1 | Coffee aroma with improved stability | SYMRISE AG (DE) | 2004-10-14 | — | — | US | claimed |
| US-20080317824-A1 | Chocolate Coated Spherical Filled Capsules | SYMRISE GMBH & CO. KG (DE) | 2008-12-25 | — | — | US | disclosed |
| EP-1940363-A2 | CHOCOLATE COATED SPHERICAL FILLED CAPSULES | Symrise GmbH & Co. KG (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-7316826-B2 | Coffee aroma with improved stability | SYMRISE GMBH & CO. KG (DE) | 2008-01-08 | — | — | US | disclosed |
| WO-2007020262-A2 | CHOCOLATE COATED SPHERICAL FILLED CAPSULES | SYMRISE GMBH & CO. KG (DE) | 2007-02-22 | — | — | WO | disclosed |
| US-20040202767-A1 | Coffee aroma with improved stability | SYMRISE AG (DE) | 2004-10-14 | — | — | US | disclosed |