Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | APLNR | P35414 | 1/20 | 0.36 |
| ▸ | GLP1R | P43220 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | TACR1 | P25103 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.30 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL7750351 | 0.98 | ADRB2 (0.37) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL4631313 | 0.91 | ADRB2 (0.37) | ADRB2FPR1GPR183APLNRGLP1R | |
| Water SCHEMBL7749198 | 0.89 | ADRB2 (0.38) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL4630773 | 0.81 | TACR1 (0.38) | ADRB2FPR1GPR183APLNRGLP1R | |
| Water SCHEMBL7749169 | 0.80 | TACR1 (0.37) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL7750393 | 0.80 | ADRB2 (0.39) | ADRB2FPR1GPR183APLNRGLP1R | |
| SCHEMBL4631605 | 0.80 | TACR1 (0.34) | CYP3A4ALDH1A1CYP2D6SMN1; SMN2TACR1 | |
| SCHEMBL4630794 | 0.79 | HSD11B1 (0.34) | ADRB2FPR1GPR183APLNRGLP1R | |
| Hydrochloric Acid SCHEMBL7750338 | 0.79 | ADRB2 (0.34) | ADRB2FPR1GPR183APLNRGLP1R | |
| Water SCHEMBL7749122 | 0.79 | TACR1 (0.34) | CYP3A4ALDH1A1CYP2D6SMN1; SMN2TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1923391-A1 | Substituted heterocyclic compounds, method for preparing same and pharmaceutical compositions containing them. | sanofi-aventis (FR) | 2008-05-21 | — | — | EP | disclosed |
| EP-1340754-A1 | Substituted heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them | SANOFI-SYNTHELABO (FR) | 2003-09-03 | — | — | EP | disclosed |
| EP-1156049-A1 | Substituted heterocyclic compounds, their process of preparation and pharmaceutical compositions containing them | SANOFI-SYNTHELABO (FR) | 2001-11-21 | — | — | EP | disclosed |
| WO-1996023787-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SANOFI (FR) | 1996-08-08 | — | — | WO | disclosed |