Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tert-Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylamine SCHEMBL202768 | 0.89 | THRB (0.59) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Chloromethane SCHEMBL17453350 | 0.89 | THRB (0.59) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Hydroxyamine SCHEMBL29435122 | 0.89 | THRB (0.59) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL19409375 | 0.89 | THRB (0.64) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| SCHEMBL15030 | 0.89 | — | — | |
| Acetamide SCHEMBL28712443 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Urea SCHEMBL28331735 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Methylamine SCHEMBL28938689 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Ethylamine SCHEMBL4364175 | 0.86 | THRB (0.57) | THRBTSHRALDH1A1LMNAHSD17B10 | |
| Tert-Butylamine SCHEMBL4976478 | 0.86 | THRB (0.42) | THRBTSHRALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1024 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE50703-E1 | Polymer composition | Mitsubishi Chemical UK Limited (GB) | 2025-12-16 | — | — | US | claimed |
| US-20250136862-A1 | LIGHT EMITTING ELEMENT, DISPLAY DEVICE INCLUDING THE LIGHT EMITTING ELEMENT, AND METHOD OF MANUFACTURING THE LIGHT EMITTING ELEMENT | SAMSUNG DISPLAY CO., LTD. (KR) | 2025-05-01 | — | — | US | claimed |
| US-11370907-B2 | Polymer composition | Mitsubishi Chemical UK Limited (GB) | 2022-06-28 | — | — | US | claimed |
| US-20200231780-A1 | POLYMER COMPOSITION | Mitsubishi Chemical UK Limited (GB) | 2020-07-23 | — | — | US | claimed |
| US-10138307-B2 | Antimicrobial polymer | Fachhochschule Münster (DE) | 2018-11-27 | — | — | US | claimed |
| WO-2018142164-A1 | POLYMER COMPOSITION | LUCITE INTERNATIONAL UK LIMITED (GB) | 2018-08-09 | — | — | WO | claimed |
| US-20150368380-A1 | ANTIMICROBIAL POLYMER | Fachhochschule Münster (DE) | 2015-12-24 | — | — | US | claimed |
| US-9132077-B2 | Cosmetic agent | HENKEL AG & CO. KGAA (DE) | 2015-09-15 | — | — | US | claimed |
| US-20120128619-A1 | COSMETIC AGENT | HENKELSTRASSE 67 (DE) | 2012-05-24 | — | — | US | claimed |
| US-8039568-B2 | Comprise ethyl methacrylate, at least one alpha , beta -ethylenically unsaturated amide group-containing compound and at least one monoethylenically unsaturated carboxylic acid; cosmetic and pharmaceutical use | BASF SE (DE) | 2011-10-18 | — | — | US | claimed |
| EP-0832159-A1 | AUTOMOTIVE COATINGS FROM NON-AQUEOUS DISPERSIONS | THE SHERWIN-WILLIAMS COMPANY (US) | 1998-04-01 | — | — | EP | claimed |
| EP-0714921-B1 | Cationic fluorinated copolymers for oil and water repellent treatment of construction materials | ATOCHEM ELF SA (FR) | 1997-09-17 | — | — | EP | claimed |
| EP-0425436-B1 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA GEIGY AG (CH) | 1996-12-27 | — | — | EP | claimed |
| WO-1996040828-A1 | AUTOMOTIVE COATINGS FROM NON-AQUEOUS DISPERSIONS | THE SHERWIN-WILLIAMS COMPANY (US) | 1996-12-19 | — | — | WO | claimed |
| US-5516820-A | SUBSTRATE COATED WITH A MULTILAYER DECORATIVE AND/OR PROTECTIVE COATING | BABJAK JOHN R (US) | 1996-05-14 | — | — | US | claimed |
| US-5079319-A | Contact Lenses | CIBA-GEIGY CORPORATION (US) | 1992-01-07 | — | — | US | claimed |
| EP-0425436-A2 | Reactive silicone and/or fluorine containing hydrophilic prepolymers and polymers thereof | CIBA-GEIGY AG (CH) | 1991-05-02 | — | — | EP | claimed |
| US-5010141-A | Heat- or UV-curable acrylic resins; coatings; films; biocompatible, water-swelling, oxygen-permeable contact lenses | CIBA-GEIGY CORPORATION (US) | 1991-04-23 | — | — | US | claimed |
| US-4299752-A | A DISPERSION OF AN ADDITION POLYMER CONTAINING METALLIC PIGMENTATION IN AN ORGANIC LIQUID AND A COALESCING SOLVENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-11-10 | — | — | US | claimed |
| US-4259231-A | ACRYLIC ISOCYANATE CURABLE WITH MOISTURE | NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1981-03-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10138307-B2 | Antimicrobial polymer | PUF60, PARG, DPM1 | THRB 4808/4885TSHR 4853/4885ALDH1A1 3068/4885 |
| US-20120128619-A1 | COSMETIC AGENT | KRT18, PRKDC, POLR1C | THRB 4496/4885TSHR 3858/4885ALDH1A1 2927/4885 |
| US-20150368380-A1 | ANTIMICROBIAL POLYMER | PUF60, PARG, DPM1 | THRB 4808/4885TSHR 4853/4885ALDH1A1 3068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.