Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 10/20 | 0.42 |
| ▸ | HTR2C | P28335 | 3/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20767132 | 0.90 | ALDH1A1 (0.45) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL4630869 | 0.84 | MEN1 (0.62) | ALDH1A1MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL20767017 | 0.74 | KDM4E (0.54) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL20562467 | 0.72 | TAAR1 (0.66) | HTR2AHTR2CHTR2B | |
| SCHEMBL34463042 | 0.72 | TAAR1 (0.66) | HTR2AHTR2CHTR2B | |
| SCHEMBL27678560 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL27766249 | 0.72 | KMT2A (0.59) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL1678515 | 0.71 | ALDH1A1 (0.60) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL26014131 | 0.71 | HTR2A (0.66) | ALDH1A1MEN1GAAKMT2ALMNA | |
| SCHEMBL17006155 | 0.71 | TAAR1 (0.44) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470103-B1 | AMIDOACETONITRILE DERIVATIVES | NOVARTIS AG (CH) | 2008-05-14 | — | — | EP | disclosed |
| US-7153814-B2 | Amidoacetonitrile derivatives | NOVARTIS ANIMAL HEALTH US, INC. (US) | 2006-12-26 | — | — | US | disclosed |
| US-20050059736-A1 | Amidoacetonitrile derivatives | NOVARTIS ANIMAL HEALTH US, INC. | 2005-03-17 | — | — | US | disclosed |
| EP-1470103-A1 | AMIDOACETONITRILE DERIVATIVES | Novartis AG (CH) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003059868-A1 | AMIDOACETONITRILE DERIVATIVES | NOVARTIS AG (CH) | 2003-07-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059736-A1 | Amidoacetonitrile derivatives | ARG1, NAT1, NMBR | ALDH1A1 776/4885MEN1 322/4885GAA 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.