Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.41 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1864716 | 1.00 | LMNA (0.62) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| Hydrochloric Acid SCHEMBL11848398 | 0.98 | LMNA (0.60) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL4463734 | 0.98 | LMNA (0.59) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8393529 | 0.93 | — | — | |
| SCHEMBL1444507 | 0.87 | — | — | |
| SCHEMBL1669840 | 0.83 | LMNA (0.59) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL276585 | 0.82 | LMNA (0.46) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL23129641 | 0.81 | LMNA (0.57) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8393247 | 0.81 | LMNA (0.57) | LMNASLC1A3SLC1A2SLC1A1PARP15 | |
| SCHEMBL8394920 | 0.81 | LMNA (0.57) | LMNASLC1A3SLC1A2SLC1A1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1698684-B1 | Alkyl cycloheptylmethyl carbonates and perfume compositions | KAO CORP (JP) | 2008-05-14 | — | — | EP | claimed |
| US-5864043-A | CARDIOVASCULAR DISORDERS AND ANGIOTENSIN ANTAGONIST | KARL THOMAE GMBH (DE) | 1999-01-26 | — | — | US | disclosed |
| US-5541229-A | ANGIOITENSIN II ANTAGONIST AS HYPOTENSIVE AGENTS, ANTIISCHEMIC AGENTS AND CARDIOVASCULAR DISORDERS | DR. KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |