⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17030089 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL27882889 | 0.98 | LMNA (0.36) | — | |
| Hydrochloric Acid SCHEMBL17022784 | 0.98 | LMNA (0.36) | — | |
| SCHEMBL17030143 | 0.81 | THRB (0.40) | — | |
| SCHEMBL15373451 | 0.78 | — | — | |
| SCHEMBL15373196 | 0.78 | — | — | |
| SCHEMBL17029961 | 0.78 | PTPN1 (0.35) | — | |
| SCHEMBL17523047 | 0.77 | MEN1 (0.30) | — | |
| SCHEMBL17029985 | 0.76 | THRB (0.40) | — | |
| SCHEMBL14700172 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3430000-B1 | PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR | AFFERENT PHARMACEUTICALS INC (US) | 2022-12-28 | — | — | EP | disclosed |
| US-10822311-B2 | Pyrimidines and variants thereof, and uses therefor | Afferent Pharmaceuticals, Inc. (US) | 2020-11-03 | — | — | US | disclosed |
| WO-2017160569-A1 | PYRIMIDINES AND VARIANTS THEREOF, AND USES THEREFOR | AFFERENT PHARMACEUTICALS INC. (US) | 2017-09-21 | — | — | WO | disclosed |
| US-20150250217-A1 | SALTY TASTE-ENHANCING AGENT AND MANUFACTURING METHOD THEREFOR, AND SALTY TASTE-ENHANCING METHOD | NISSAN FOODS HOLDINGS CO., LTD. (JP) | 2015-09-10 | — | — | US | disclosed |
| EP-2910130-A1 | SALTY TASTE-ENHANCING AGENT AND MANUFACTURING METHOD THEREFOR, AND SALTY TASTE-ENHANCING METHOD | Nissin Foods Holdings Co., Ltd. (JP) | 2015-08-26 | — | — | EP | disclosed |
| EP-1924565-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P3X2/3 MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007025900-A1 | DIAMINOPYRIMIDINES AS P2X3 AND P3X2/3 MODULATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-08 | — | — | WO | disclosed |
| WO-2000012454-A9 | NOVEL POLYCATIONIC LIPIDS | HACES ALBERTO (US) | 2000-06-15 | — | — | WO | disclosed |
| WO-2000012454-A1 | NOVEL POLYCATIONIC LIPIDS | HACES ALBERTO (US) | 2000-03-09 | — | — | WO | disclosed |
| WO-1997042819-A9 | CATIONIC LIPIDS FOR TRANSFECTION OF NEGATIVELY CHARGED OR NEUTRAL MOLECULES INTO LIVING CELLS | — | 1998-03-12 | — | — | WO | disclosed |
| WO-1997042819-A1 | CATIONIC LIPIDS FOR TRANSFECTION OF NEGATIVELY CHARGED OR NEUTRAL MOLECULES INTO LIVING CELLS | HACES ALBERTO (US) | 1997-11-20 | — | — | WO | disclosed |