Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.46 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.44 |
| ▸ | GLRB | P48167 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27923138 | 0.98 | TDP1 (0.57) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL27888034 | 0.98 | TDP1 (0.57) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL27904859 | 0.96 | TDP1 (0.56) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL31350139 | 0.88 | TDP1 (0.50) | TDP1RXRBNR1H4SRD5A2NPC1 | |
| SCHEMBL17470866 | 0.86 | CES2 (0.59) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL5873299 | 0.86 | TDP1 (0.57) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL31528338 | 0.85 | TDP1 (0.71) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL1356449 | 0.85 | TDP1 (0.71) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL28432778 | 0.84 | TDP1 (0.44) | TDP1RXRBNR1H4SRD5A2AKR1C2 | |
| SCHEMBL162565 | 0.83 | RXRB (0.69) | TDP1RXRBNR1H4SRD5A2AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112852014-B | Asymmetric organic aromatic ligand metal salt nucleating agent and preparation method and application thereof | 华东理工大学 | 2022-03-15 | — | — | CN | claimed |
| CN-112852014-A | Asymmetric organic aromatic ligand metal salt nucleating agent and preparation method and application thereof | 华东理工大学 | 2021-05-28 | — | — | CN | claimed |
| CN-112852014-B | Asymmetric organic aromatic ligand metal salt nucleating agent and preparation method and application thereof | 华东理工大学 | 2022-03-15 | — | — | CN | disclosed |
| CN-112852014-A | Asymmetric organic aromatic ligand metal salt nucleating agent and preparation method and application thereof | 华东理工大学 | 2021-05-28 | — | — | CN | disclosed |
| CN-105348310-A | Preparation method for nucleating agent | GCH TECHNOLOGY CO LTD | 2016-02-24 | — | — | CN | disclosed |
| US-20150344627-A1 | LOW MODULUS NEGATIVE TONE, AQUEOUS DEVELOPABLE PHOTORESIST | DESIGNER MOLECULES, INC | 2015-12-03 | — | — | US | disclosed |
| CN-104610720-A | High-impact high-density PC/ABS alloy and preparation method thereof | GUANGDONG TIANBAO NEW MATERIAL CO LTD | 2015-05-13 | — | — | CN | disclosed |
| US-8778874-B2 | Glycopeptide antibiotic monomer derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| CN-102850578-B | Nucleator composition, its preparation method and polypropylene material | CHINA PETROLEUM & CHEMICAL | 2013-11-06 | — | — | CN | disclosed |
| CN-102850578-A | Nucleator composition, its preparation method and polypropylene material | CHINA PETROLEUM & CHEMICAL | 2013-01-02 | — | — | CN | disclosed |
| EP-1923449-A1 | Colloidal suspensions of nanoscale particles | Koninklijke Philips Electronics N.V. (NL) | 2008-05-21 | — | — | EP | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
| EP-0507576-A1 | Polypropylene-based resin compositions | TOSOH CORPORATION (JP) | 1992-10-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | TDP1 4683/4885RXRB 376/4885NR1H4 33/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.